WormMine: ExpressionPattern Expr1624

• Pattern: lacZ and gfp fusions with the mec-5 promoter (TU#233 and TU#234, respectively) and a lacZ fusion with part of the mec-5 coding sequence and a sequence for a synthetic transmembrane domain (TU#235) gave the same pattern of expression with strong expression by hypodermal cells. In newly hatched animals, MEC-5 is strongly expressed by seam cells (epidermal stem cells) along the body and by hypodermal cells in the head. As the animals mature and the seam cells divide, MEC-5 is expressed by both seam cells and their progeny, but at a lower level than in newly hatched larvae. In early L2 larvae, staining is also seen in the cells of the ventral hypodermis. Strong staining is limited to the head in adults.
• Primary Identifier: Expr1624
• Remark: Reporter gene fusion type not specified.

2 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
Epidermal layer.	hypodermis	epidermis	WBbt:0005733
a group of hypodermal cells that lie along the apical midline of the hypodermis, at the extreme left and right sides between nose and tail	seam cell	lateral hypodermis	WBbt:0005753

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00003169	mec-5	E03G2.3	Caenorhabditis elegans

1 Life Stages

Remark	Definition	Other Name	Public Name	Primary Identifier
	A developemental life stage of the nematode Caenorhabditis elegans that occurs from egg hatching until death.		postembryonic Ce	WBls:0000022