WormMine: ExpressionPattern Expr14701

• Pattern: With the expression of GFP::his-58 under the control of the putative endogenous timp-1 5'-cis regulatory region, we found green fluorescence in different types of cells, i.e., epidermal cells, seam cells (lateral epidermal cells), lateral region vulval cells, and a subpopulation of head neurons, which suggested that timp-1 had been transcribed in these cells; conversely, green fluorescence was not detected in muscle cells. We confirmed that the timp-1 promoter was inactive in muscle cells by showing that GFP::HIS-58 under the control of the timp-1 promoter was not co-expressed with the mCherry muscle marker oxIs322[myo-3p::mCherry::H2B]. Although TIMP-1::Venus was detected on the gonadal basement and plasma membrane of the germ cells, GFP::HIS-58 under the control of the timp-1 promoter was not detected in gonadal somatic cells or in germ cells.
• Primary Identifier: Expr14701

4 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
Epidermal layer.	hypodermis	epidermis	WBbt:0005733
neuron with its cell body situated in the head, excluding the pharynx.	head neuron		WBbt:0006751
a group of hypodermal cells that lie along the apical midline of the hypodermis, at the extreme left and right sides between nose and tail	seam cell	lateral hypodermis	WBbt:0005753
Constituent cell of a hermaphrodite vulva.	vulval cell	vulval epithelial cell	WBbt:0007831

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00019476	timp-1	K07C11.3	Caenorhabditis elegans

0 Life Stages