WormMine: ExpressionPattern Expr15836

• Pattern: PAN-1GFP signal was detected broadly in embryos and early larvae, but decreased substantially in late larvae and adults. Two types of PAN-1GFP subcellular patterns were observed: at the cell membrane and as cytoplasmic puncta. Some prominent PAN-1GFP signal was found in seam cells, a type of epidermal cells that shows stem-cell like division during larval development. These cells were lined up in a single profile at each lateral line and embedded in syncytial epidermis. Between the seam cells and the epidermis, a ring of tight junctions formed on the apical-lateral side of the cells. By colabelling a tight-junction component DLG-1::RFP and PAN-1GFP, we observed that PAN-1 distributed at the lateral basal membrane of seam cells. PAN-1 is also localized on the cell membrane of many ventral cord neurons, including DD neurons at L1 and L2. Therefore, we observed that PAN-1 is localized on the cell membrane.
• Primary Identifier: Expr15836

1 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
a group of hypodermal cells that lie along the apical midline of the hypodermis, at the extreme left and right sides between nose and tail	seam cell	lateral hypodermis	WBbt:0005753

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00003915	pan-1	M88.6	Caenorhabditis elegans

3 Life Stages

Remark	Definition	Other Name	Public Name	Primary Identifier
	The stage that begins when a C.elegans individual is fully-developed and has reached maturity.		adult Ce	WBls:0000041
	The whole period of embryogenesis in the nematode Caenorhabditis elegans, from the formation of an egg until hatching.		embryo Ce	WBls:0000003
	A developmental life stage of the nematode Caenorhabditis elegans that occurs from egg hatching until adulthood.		larva Ce	WBls:0000023