WormMine: ExpressionPattern Expr10008

• Pattern: Consistent colocalization of GFP and RFP was observed between Pfmi-1-gfp and Pacr-2-rfp in the DA, VA, and VB and weakly in the DB cholinergic neurons. We occasionally observed a limited coexpression of Punc-25- rfp and Pfmi-1-gfp in the DDs of some L1 animals (<10%), but never in the VDs (>L2).
• Primary Identifier: Expr10008
• Subcellular Localization: FMI-1 accumulated to a region of neuropil around the nerve ring and the ventral cord. FMI-1 was also present in the dorsal cord in young animals but was rarely observed in neuronal cell bodies. In wild-type animals, FMI-1 was concentrated in the nervous system but did not overlap with a marker of synaptic vesicles (SNT-1). Thus, our data suggest that FMI-1 is primarily present in nonsynaptic regions of the ventral cord. However, because of the en passant organization of synapses formed in the ventral nerve cord, it is not possible to determine where FMI-1 is localized with single axon/synapse resolution.

9 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
a large process bundle that runs along the vental mid-line extending from the ventral region of the nerve ring.	ventral nerve cord	ventral cord	WBbt:0005829
Complement of nervous tissue (neurones, nerves, receptors and support cells) serving to detect, relay and coordinate information about an animal`s internal and external environments and to initiate and integrate its effector responses and activities.	nervous system		WBbt:0005735
Neuron class of six motoneurons, with cell bodies in the ventral cord, which innervate dorsal muscles. Each cell has a short, posteriorly directed and a longer, anteriorly directed process emanating from its cell body. The anterior process has a branch, which leaves the ventral cord as a commissure and runs round to the dorsal cord.	DD neuron		WBbt:0005270
Neuron class of seven motoneurons that innervate dorsal muscles and have cell bodies in the ventral cord.	DB neuron		WBbt:0005274
Neuron class of twelve motoneurons, distributed along the ventral cord, which innervate ventral body muscles.	VA neuron		WBbt:0005339
Neuron class of eleven motoneurons, distributed along the ventral cord, which innervate ventral body muscles.	VB neuron		WBbt:0005336
Neuron class of nine ventral cord motor neuron, innervates dorsal muscle.	DA neuron		WBbt:0005278
the most extensive region of neuropil in the animal, consists of a large toroidal bundle of processes.	nerve ring	circumpharyngeal nerve ring	WBbt:0006749
a bundle of nerve processes that runs along the dorsal mid-line of the animal.	dorsal nerve cord	dorsal cord	WBbt:0006750

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00001475	fmi-1	F15B9.7	Caenorhabditis elegans

0 Life Stages