WormMine: ExpressionPattern Expr15097

• Pattern: Expression of MLT-2, MLT-3, and MLT-4 genes was detected exclusively within the epidermis, including hyp7, beginning in late embryogenesis. MLT- 2::mKate2 and MLT-4::GFP displayed similar patterns of expression at the epidermal apical surface within well-separated puncta and also showed strong accumulation at the boundary of hyp7 and seam cells. In more medial planes, both MLT-2 and MLT-4 were more evenly dispersed throughout the cytosol with reduced accumulation at the seam cell boundary. In contrast, accumulation of MLT-3::mKate2 was not highly enriched at the hyp7-seam cell boundary. Like MLT-2 and MLT-4, MLT-3 was expressed in apical puncta, although its expression was stronger and typically more dispersed than that observed for MLT-2 and MLT-4. In medial planes, expression of MLT-2, MLT-3, and MLT-4 was largely excluded from nuclei, but in some cases the tagged proteins exhibited partial enrichment or exclusion within other smaller compartments. Expression of MLT-2, MLT-3, and MLT-4 genes was detected exclusively within the epidermis, including hyp7, beginning in late embryogenesis. MLT-2::mKate2 and MLT-4::GFP displayed similar patterns of expression at the epidermal apical surface within well-separated puncta and also showed strong accumulation at the boundary of hyp7 and seam cells. In more medial planes, both MLT-2 and MLT-4 were more evenly dispersed throughout the cytosol with reduced accumulation at the seam cell boundary. In contrast, accumulation of MLT-3::mKate2 was not highly enriched at the hyp7-seam cell boundary. Like MLT-2 and MLT-4, MLT-3 was expressed in apical puncta, although its expression was stronger and typically more dispersed than that observed for MLT-2 and MLT-4. In medial planes, expression of MLT-2, MLT-3, and MLT-4 was largely excluded from nuclei, but in some cases the tagged proteins exhibited partial enrichment or exclusion within other smaller compartments.
• Primary Identifier: Expr15097

2 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
Epidermal layer.	hypodermis	epidermis	WBbt:0005733
entire syncytium of hyp7	hyp7 syncytium	hyp7	WBbt:0005734

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00007252	mlt-2	C01H6.2	Caenorhabditis elegans

3 Life Stages

Remark	Definition	Other Name	Public Name	Primary Identifier
	The stage that begins when a C.elegans individual is fully-developed and has reached maturity.		adult Ce	WBls:0000041
	The C. elegans life stage spanning 620-800min(hatch) after first cleavage at 20 Centigrade. Cell number remains at ~560 cells, with some new cells generated and some cells go through programmed cell death. A stage after elongation is over. The last stage of embryogenesis. Also called pre-hatched embryo, late embryo or morphogenetic embryo.		fully-elongated embryo Ce	WBls:0000021
	A developmental life stage of the nematode Caenorhabditis elegans that occurs from egg hatching until adulthood.		larva Ce	WBls:0000023