WormMine: ExpressionPattern Expr1822

• Pattern: The apical-basal polarity of the PAR proteins persists through early gastrulation, cells in the interior of the embryo accumulate PAR-6 on their blastocoel-facing surfaces; these and later changes in PAR distribution were not analyzed further.
• Primary Identifier: Expr1822
• Remark: Previous data: analysis of the PAR proteins has focused primarily on their anterior-posterior localization at the 1-cell stage and their roles in subsequent anterior-posterior polarity. After cell division begins, however, this anterior-posterior asymmetry is reiterated only in the lineage of cells that form the germline. In contrast, some somatic (non-germline) cells show an apical-basal polarity in PAR localization.
• Subcellular Localization: By the middle of the 4-cell stage, the anterior PAR protein PAR-6 is present over the entire cortex of each somatic blastomere. However by the end of the 4-cell stage and at later stages PAR-6 is concentrated in a broad `cap' centered on the apical surface.

4 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
embryonic cell	ABa		WBbt:0005906
embryonic cell	ABp		WBbt:0005994
embryonic cell	EMS		WBbt:0006876
embryonic founder cell	Psub1	lineage name: P0.p	WBbt:0006874

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00003921	par-6	T26E3.3	Caenorhabditis elegans

1 Life Stages

Remark	Definition	Other Name	Public Name	Primary Identifier
	The C. elegans life stage spanning 0-100min after first cleavage at 20 Centigrade. Proliferate from 1 cell to 28 cells. From first cleavage until the start of gastrulation.		blastula embryo Ce	WBls:0000005