WormMine: ExpressionPattern Expr1558

• Primary Identifier: Expr1558
• Remark: No detailed description on cellular expression pattern at later stages.
• Subcellular Localization: No staining was seen in gonads or unfertilized oocytes. The PAR-3 protein was first detected at the cell periphery in fertilized eggs during the meiotic divisions. In 10 out of 13 positively stained embryos, the protein was undetectable in the posterior third of the embryo. stained very strongly on the lateral periphery, and stained weakly at the periphery at the extreme anterior pole. The other embryos showed uniform peripheral staining. After meiosis II is completed and as the pronuclei start to decondense, PAR-3 is restricted to the anterior periphery at all cases, extending to about 65% of the total length of the embryo. As pronuclear migration processes, PAR-3 become more concentrated at the anterior pole, extending to about 54% of the embryonic length. During prophase, metaphase, and early anaphase of the first mitosis, the signal is strongest and extends to 48% embryo length. In addition to peripheral staining, at all stages, unlocalized PAR-3 appears to be present in the cytoplasm.

3 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
Single cell zygote	P0	lineage name: Z	WBbt:0004422
Embryonic founder cell	AB	AB blastomere	WBbt:0004015
embryonic founder cell	Psub1	lineage name: P0.p	WBbt:0006874

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00003918	par-3	F54E7.3	Caenorhabditis elegans

2 Life Stages

Remark	Definition	Other Name	Public Name	Primary Identifier
	The C. elegans life stage spanning 0-20min after first cleavage at 20 Centigrade. Contains 2 cells.		2-cell embryo Ce	WBls:0000007
	Also called zygote. -50min till 0min of first cleavage at 20 Centigrade. Contains 1 cell.		1-cell embryo Ce	WBls:0000006