WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

Expression Pattern :

Pattern  INS-18 was expressed in head and tail neurons at every developmental stage. At the dauer stage, INS-18::VENUS was more intensively expressed in head and tail neurons than at normal developmental stages. It was also expressed in ventral cells. This expression was never seen at any developmental stage. During recovery from the dauer stage, INS-18::VENUS expression gradually weakened. In 5 days after worms reached the young adult stage, we observed INS-18::VENUS expression in pairs of ventral cells near the vulva. Based on their shape and anatomical location, we speculate these cells to be HSNs To support this hypothesis, we analyzed INS-18 expression in male transgenic worms. These worms expressed INS-18::VENUS only in head and tail neurons and not in ventral cells. Therefore, we concluded that INS-18::VENUS is expressed in HSNs at the adult stage. Primary Identifier  Expr10100
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4 Anatomy Terms

Definition Name Synonym Primary Identifier
neuron with its cell body situated in the head, excluding the pharynx. head neuron   WBbt:0006751
neuron with its cell body situated in the tail, posterior to rectum. tail neuron   WBbt:0006759
Herm. specific motor neurons (die in male embryo), innervate vulval muscles, serotonergic HSNL lineage name: ABplapppappa WBbt:0004758
Herm. specific motor neurons (die in male embryo), innervate vulval muscles, serotonergic HSNR lineage name: ABprapppappa WBbt:0004757

1 Genes

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00002101 ins-18 T28B8.2 Caenorhabditis elegans

6 Life Stages

Remark Definition Other Name Public Name Primary Identifier
  The fourth stage larva. At 25 Centigrade, it ranges 40-49.5 hours after fertilization, 26-35.5 hours after hatch. L4 larva Ce WBls:0000038
  The first stage larva. At 25 Centigrade, it ranges 14-25.5 hours after fertilization, 0-11.5 hours after hatch. L1 larva Ce WBls:0000024
  The stage that begins when a C.elegans individual is fully-developed and has reached maturity. adult Ce WBls:0000041
  The third stage larva. At 25 Centigrade, it ranges 32.5-40 hours after fertilization, 18.5-26 hours after hatch. L3 larva Ce WBls:0000035
  The second stage larva. At 25 Centigrade, it ranges 25.5-32.5 hours after fertilization, 11.5-18.5 hours after hatch. L2 larva Ce WBls:0000027
  A third stage larva specialized for dispersal and long term survival. dauer larva Ce WBls:0000032