| Pattern | Expressed in most, if not all cells. | Primary Identifier | Expr3978 |
| Remark | Five stable lines were produced, all of which show identical expression patterns. | Subcellular Localization | NPP-1::GFP is localized to the nuclear envelope of most, if not all cells of transgenic animals. This is consistent with the expected localization of a nucleoporin. There is no evidence for developmental regulation of npp-1 because all cells in all stages of development express NPP-1::GFP. Signal is detected at pronuclear formation and is found on the nuclear envelope of both the maternal and paternal pronucleus. Signal disappears at pronuclear breakdown, but returns to the nuclear envelope as the envelope reforms during telophase. There is also some punctate cytoplasmic GFP signal that can be observed moving in the cytoplasm. These punctuate cytoplasmic signals may be an artifact of expressing GFP because similar patterns are seen with negative control constructs. There are also frequently punctate GFP signals inside the nucleus which are not apparent in the GFP-only control lines. |
| Definition | Name | Synonym | Primary Identifier |
|---|---|---|---|
| a cellular object that consists of subcellular components, expresses genes or functions. | Cell | Cell type | WBbt:0004017 |
| WormBase Gene ID | Gene Name | Sequence Name | Organism |
|---|---|---|---|
| WBGene00003787 | npp-1 | K07F5.13 | Caenorhabditis elegans |
