WormMine: ExpressionPattern Expr1281

• Pattern: In wild-type larvae, LET-23 RTK is first expressed in the vulval precursor cells in the early L2 stage. LET-23 staining is observed throughout the basolateral membrane of all six vulval precursor cells. In five of the vulval precursor cells (P3.p, P4.p, P5.p, P7.p, and P8.p), little or no LET-23 is present in the apical membrane domain. In the remaining vulval precursor cell (P6.p), LET-23 is present in both the basolateral and apical membrane domains. As P6.p divides in early L3, LET-23 staining continues to be present in both the basolateral and apical membrane domains.
• Primary Identifier: Expr1281
• Subcellular Localization: Appears on both the basolateral and apical membrane domains, with higher levels in the apical membrane domain.

6 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
	P6.p hermaphrodite		WBbt:0008125
descendent cell of post-embryonic blast cell P5, posterior, in hermaphrodite.	P5.p hermaphrodite		WBbt:0008121
descendent cell of post-embryonic blast cell P4, posterior, in hermaphrodite.	P4.p hermaphrodite		WBbt:0008117
descendent cell of post-embryonic blast cell P3, posterior in hermaphrodite.	P3.p hermaphrodite		WBbt:0008112
	P8.p hermaphrodite		WBbt:0008133
	P7.p hermaphrodite		WBbt:0008129

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00002299	let-23	ZK1067.1	Caenorhabditis elegans

2 Life Stages

Remark	Definition	Other Name	Public Name	Primary Identifier
	The third stage larva. At 25 Centigrade, it ranges 32.5-40 hours after fertilization, 18.5-26 hours after hatch.		L3 larva Ce	WBls:0000035
	The second stage larva. At 25 Centigrade, it ranges 25.5-32.5 hours after fertilization, 11.5-18.5 hours after hatch.		L2 larva Ce	WBls:0000027