WormMine: ExpressionPattern Expr2308

• Primary Identifier: Expr2308
• Subcellular Localization: PAR-1 distribution was examined from the mid-L3 stage to young adulthood, using AJM-1 as a marker for the identity and position of vulval cells through vulval development. PAR-1 is localized near apical junctions prior to vulval development. This localization is common to other C. elegans epithelial cells. After fate specification and precursor proliferation, PAR-1 is not only found near apical junctions, but it is also associated with the cortex of the vulval cells. Through morphogenesis, PAR-1 gradually undergoes a redistribution from near apical junctions to the basolateral cortex. By young adulthood, PAR-1 is highly enriched in basolateral domains and little, if any, is still found associated with junctions. The PAR-1 distribution was identical using three different sources of antibodies to PAR-1 and, was sensitive to par-1(RNAi).

1 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
female genital.	vulva		WBbt:0006748

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00003916	par-1	H39E23.1	Caenorhabditis elegans

3 Life Stages

Remark	Definition	Other Name	Public Name	Primary Identifier
	The fourth stage larva. At 25 Centigrade, it ranges 40-49.5 hours after fertilization, 26-35.5 hours after hatch.		L4 larva Ce	WBls:0000038
	The third stage larva. At 25 Centigrade, it ranges 32.5-40 hours after fertilization, 18.5-26 hours after hatch.		L3 larva Ce	WBls:0000035
	The stage after an hermaphrodite animal is fully-developed and reaches maturity.		adult hermaphrodite Ce	WBls:0000057