1 Genes
| WormBase Gene ID | Gene Name | Sequence Name | Organism |
|---|---|---|---|
| WBGene00004367 | ric-8 | Y69A2AR.2 | Caenorhabditis elegans |
| Primary Identifier | Expr3105 | Subcellular Localization | The bulk of the signal is cytoplasmic in one-cell stage embryos, with a slight enrichment in the vicinity of microtubule asters. In addition, some signal is present at the cell cortex, something that is more apparent in two- or four-cell stage embryos. The cytoplasmic and cortical distributions correspond to bona fide RIC-8 because they are significantly diminished in ric-8(RNAi) embryos. RIC-8 antibodies also decorate the nuclear periphery, but this signal does not appear specific because it is still present in ric-8(RNAi) embryos, a conclusion also reached when examining neurons. The distribution of RIC-8 is not altered in ric-8(md1909) or ric-8(md303) mutant embryos, nor in goa-1/gpa-16(RNAi) or gpr-1/2(RNAi) embryos. Taken together, these observations indicate that the bulk of RIC-8 in early embryos is cytoplasmic, although a fraction of the protein is found at the cell cortex. |
| WormBase Gene ID | Gene Name | Sequence Name | Organism |
|---|---|---|---|
| WBGene00004367 | ric-8 | Y69A2AR.2 | Caenorhabditis elegans |
