1 Genes
| WormBase Gene ID | Gene Name | Sequence Name | Organism |
|---|---|---|---|
| WBGene00004130 | ketn-1 | F54E2.3 | Caenorhabditis elegans |
| Primary Identifier | Expr3812 | Remark | This pattern is inconsistent with the report by Kolmerer and colleagues that a monoclonal antibody against insect kettin recognizes the dense bodies in the C. elegans body wall muscle. Furthermore, the MH44 staining significantly extends into the I-bands towards the A-bands, whereas kettin in insects or crayfish localizes in or near the Z-discs. Therefore, further studies on the localization of C. elegans kettin are needed to determine if these discrepancies are due to different epitopes recognized by the antibodies or inherent unique characteristics of C. elegans kettin that might be adapted to the obliquely striated muscle. |
| Subcellular Localization | Kettin co-localized with actin in a ladder-like pattern, but the width of the staining was narrower than the actin bands. Vinculin, a component of the dense bodies, localized to the spots where the kettin staining was very weak or absent. Therefore, kettin is associated with a portion of the thin filaments near the dense bodies, which are equivalent to the Z-discs in cross-striated muscles. |
| WormBase Gene ID | Gene Name | Sequence Name | Organism |
|---|---|---|---|
| WBGene00004130 | ketn-1 | F54E2.3 | Caenorhabditis elegans |
