WormMine

WS294

Intermine data mining platform for C. elegans and related nematodes

Expression Pattern :

Pattern  The alpha-PKD-2 antibodies stained only male-specific sensory neurons in wild-type animals. Based on cell body positions, the PKD-2 protein is detected in the head CEMs, ray (except Ray 6), and hook HOB neurons of wild-type males. Primary Identifier  Expr2409
Remark  The overall pattern of alpha-PKD-2 antibody staining is consistent with the expression of the pkd-2::gfp4 fusion gene, although there are a few differences. First, alpha -PKD-2 antibodies label only male-specific neurons, whereas pkd-2::gfp4 is additionally expressed in non-sex-, non-stage-specific nerve ring neurons and occasionally in ray structural cells. Second, alpha-PKD-2 antibodies also recognize axons of male-specific sensory neurons, whereas pkd-2::gfp4 is only weakly expressed in axons. pkd-2(sy606 deletion) mutant animals exhibited no immunoreactivity, demonstrating the specificity of our alpha-PKD-2 polyclonal antibody. Subcellular Localization  The alpha-PKD-2 antibodies labeled the entire neuron (cilia, dendrite, cell body, and axon). Cytoplasmic, nonnuclear staining in cell bodies and dendrites is punctate, suggesting that one pool of PKD-2 is located in intracellular membranes of the ER, Golgi apparatus, and/or transport vesicles while another is found in sensory cilia.
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37 Anatomy Terms

Definition Name Synonym Primary Identifier
Post-embryonic cell of pedigree V6L.pppapaaa, male sensory rays, neuron, striated rootlet. R4AL lineage name: V6L.pppapaaa WBbt:0004030
Post-embryonic cell of pedigree V6R.pppapaaa, male sensory rays, neuron, striated rootlet. R4AR lineage name: V6R.pppapaaa WBbt:0004029
Post-embryonic cell of pedigree V6L.papapaaa, male sensory rays, neuron, striated rootlet. R2AL lineage name: R2L.aaa WBbt:0004042
Post-embryonic cell of pedigree V6R.papapaaa, male sensory rays, neuron, striated rootlet. R2AR lineage name: R2R.aaa WBbt:0004041
Post-embryonic cell of pedigree V6L.papppapa, male sensory rays, neuron, darkly staining tip, open to outside. R3BL lineage name: V6L.papppapa WBbt:0004034
Post-embryonic cell of pedigree V6R.papppapa, male sensory rays, neuron, darkly staining tip, open to outside. R3BR lineage name: V6R.papppapa WBbt:0004033
Post-embryonic cell of pedigree TL.appaaapa, male sensory rays, neuron, darkly staining tip, open to outside. R8BL lineage name: TL.appaaapa WBbt:0003990
Male sensory rays, neuron, darkly staining tip, open to outside R8BR lineage name: TR.appaaapa WBbt:0003988
Post-embryonic cell of pedigree V6L.pppapapa, male sensory rays, neuron, darkly staining tip, open to outside. R4BL lineage name: V6L.pppapapa WBbt:0004028
Post-embryonic cell of pedigree V6R.pppapapa, male sensory rays, neuron, darkly staining tip, open to outside. R4BR lineage name: V6R.pppapapa WBbt:0004027
Neuron class of one male-specific sensory neuron associated with hook sensillum, receptor anterior to cloaca in male. HOB lineage name: P10.ppap WBbt:0004761
Post-embryonic cell of pedigree V6L.papapapa, male sensory rays, neuron, darkly staining tip, open to outside. R2BL lineage name: V6L.papapapa WBbt:0004040
Post-embryonic cell of pedigree V6R.papapapa, male sensory rays, neuron, darkly staining tip, open to outside. R2BR lineage name: V6R.papapapa WBbt:0004039
Male specific cephalic neurons (programmed cell death in hermaphrodite embryo) open to outside, possible function in male chemotaxis toward hermaphrodite. CEMDL lineage name: ABplaaaaaap WBbt:0004945
Male specific cephalic neurons (programmed cell death in hermaphrodite embryo) open to outside, possible function in male chemotaxis toward hermaphrodite. CEMDR lineage name: ABarpapaaap WBbt:0004943
Male specific cephalic neurons (programmed cell death in hermaphrodite embryo) open to outside, possible function in male chemotaxis toward hermaphrodite. CEMVL lineage name: ABplpaapapp WBbt:0004941
Post-embryonic cell of pedigree V5L.pppppapa, male sensory rays, neuron, darkly staining tip, open to outside. R1BL lineage name: V5L.pppppapa WBbt:0004048
Male specific cephalic neurons (programmed cell death in hermaphrodite embryo) open to outside, possible function in male chemotaxis toward hermaphrodite. CEMVR lineage name: ABprpaapapp WBbt:0004939
Post-embryonic cell of pedigree V5R.pppppapa, male sensory rays, neuron, darkly staining tip, open to outside. R1BR lineage name: V5R.pppppapa WBbt:0004046
Post-embryonic cell of pedigree TL.appapapa, male sensory rays, neuron, darkly staining tip, open to outside. R9BL lineage name: TL.appapapa WBbt:0003968
Post-embryonic cell of pedigree TL.apappapa, male sensory rays, neuron, darkly staining tip, open to outside. R7BL lineage name: TL.apappapa WBbt:0004001
Male sensory rays, neuron, darkly staining tip, open to outside R7BR lineage name: TR.apappapa WBbt:0004000
Male sensory rays, neuron, darkly staining tip, open to outside R9BR lineage name: TR.appapapa WBbt:0003966
Post-embryonic cell of pedigree V6L.ppppaapa, male sensory rays, neuron, darkly staining tip, open to outside. R5BL lineage name: V6L.ppppaapa WBbt:0004022
Post-embryonic cell of pedigree V6R.ppppaapa, male sensory rays, neuron, darkly staining tip, open to outside. R5BR lineage name: V6R.ppppaapa WBbt:0004021
Post-embryonic cell of pedigree TL.appaaaaa, male sensory rays, neuron, striated rootlet. R8AL lineage name: TL.appaaaaa WBbt:0003994
Male sensory rays, neuron, striated rootlet R8AR lineage name: TR.appaaaaa WBbt:0003992
Post-embryonic cell of pedigree V6L.ppppaaaa, male sensory rays, neuron, striated rootlet. R5AL R5L.aaa WBbt:0004024
Post-embryonic cell of pedigree V6R.ppppaaaa, male sensory rays, neuron, striated rootlet. R5AR lineage name: V6R.ppppaaaa WBbt:0004023
Post-embryonic cell of pedigree V6L.papppaaa, male sensory rays, neuron, striated rootlet. R3AL lineage name: R3L.aaa WBbt:0004036

1 Genes

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00004035 pkd-2 Y73F8A.1 Caenorhabditis elegans

0 Life Stages