WormMine: ExpressionPattern Expr1095

• Pattern: expressed in embryo, early larva stage and adult male and hermaphrodites in the germ cells.
• Primary Identifier: Expr1095
• Subcellular Localization: During the first embryonic cleavage division in C. elegans, MDF-2 localized around the DNA, in the spindle region, and at the centrosomes, in a cell-cycle-dependent manner. As embryogenesis progressed and cell number increased, the intensity of the MDF-2 signals decreased. About 300 min after fertilization, strong MDF-2 staining appeared in the nuclei of gut-cell precursors in embryos. Strong staining was observed in these cells throughout the remainder of embryonic development, and during early larval stages. In both hermaphrodites and males, MDF-2 was detected in the nuclear matrix of germ cells during premeiotic proliferation and meiotic prophase. During both meiosis I and II, MDF-2 was present in the spindle pole region.

1 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
cell line which early in development becomes differentiated from the remaining somatic cell line, and alone has the potential to undergo meiosis and form gametes.	germ line	germline	WBbt:0005784

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00003161	mdf-2	Y69A2AR.30	Caenorhabditis elegans

4 Life Stages

Remark	Definition	Other Name	Public Name	Primary Identifier
	The second stage larva. At 25 Centigrade, it ranges 25.5-32.5 hours after fertilization, 11.5-18.5 hours after hatch.		L2 larva Ce	WBls:0000027
	The first stage larva. At 25 Centigrade, it ranges 14-25.5 hours after fertilization, 0-11.5 hours after hatch.		L1 larva Ce	WBls:0000024
	The stage that begins when a C.elegans individual is fully-developed and has reached maturity.		adult Ce	WBls:0000041
	The whole period of embryogenesis in the nematode Caenorhabditis elegans, from the formation of an egg until hatching.		embryo Ce	WBls:0000003