WormMine: ExpressionPattern Expr11703

• Pattern: In larval stages, TOP-1b protein was detected in nuclei of many cells. TOP-1b protein was also localized in the distal tip cells (DTC).
• Primary Identifier: Expr11703
• Subcellular Localization: TOP-1b protein was mostly localized to nuclei throughout embryogenesis, and the concentration was comparatively higher in the nucleoli of embryo's gut cells. In C. elegans germline, TOP-1b was localized to the nuclei of germ cells and oocytes and expression levels were comparatively higher in the nucleoli than in the nucleoplasm of oocytes.

1 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
somatic cell that situates at the tip of a gonad arm.	distal tip cell	DTC	WBbt:0006865

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00006595	top-1	M01E5.5	Caenorhabditis elegans

2 Life Stages

Remark	Definition	Other Name	Public Name	Primary Identifier
	The whole period of embryogenesis in the nematode Caenorhabditis elegans, from the formation of an egg until hatching.		embryo Ce	WBls:0000003
	A developmental life stage of the nematode Caenorhabditis elegans that occurs from egg hatching until adulthood.		larva Ce	WBls:0000023