WormMine: LifeStage WBls:0000107

• Definition: The second stage larva of nematodes.
• Primary Identifier: WBls:0000107
• Public Name: L2 larval stage

0 Anatomy Terms

1 Contained In

Remark	Definition	Other Name	Public Name	Primary Identifier
	The stage that begins after hatching and ends when the nematode becomes adult.		nematode larval stage	WBls:0000105

1 Expression Clusters

Regulated By Treatment	Description	Algorithm	Primary Identifier
Heat shock: 34C 30min.	Transcripts that showed significantly increased expression in L2 larva stage C. briggsae animals after incubated in a 34C water bath for 30min.	DESeq2 v 1.18.1, fold change > 2, FDR < 0.01.	WBPaper00058955:heatshock_upregulated_CBG

1 Expression Patterns

• Primary Identifier: Expr14445
• Pattern: lep-5 RNA was readily detectable in the tail tip of an L2 male. Co-staining with DAPI indicated that lep-5 RNA is predominantly, if not exclusively, cytoplasmic. Consistent with the broad expression of the transcriptional reporter, lep-5 RNA was also detectable throughout the body, including neuronal ganglia of the head and tail and in the developing male somatic gonad.

1 Followed By

Remark	Definition	Other Name	Public Name	Primary Identifier
	The third stage larva of nematodes.		L3 larval stage	WBls:0000108

1 Preceded By

Remark	Definition	Other Name	Public Name	Primary Identifier
	The first stage larva of nematodes.		L1 larval stage	WBls:0000106

2 Sub Stages

Remark	Definition	Other Name	Public Name	Primary Identifier
	The second stage larva. At 25 Centigrade, it ranges 25.5-32.5 hours after fertilization, 11.5-18.5 hours after hatch.		L2 larva Ce	WBls:0000027
	The second stage larva. Derived from flight muscles of vector host; some development in vitro, with L1 to L2 moulting, has been demonstrated but rarely; these are often staged by hours or days post blood meal.		Brugia L2	WBls:0000080