WormMine: RNAi WBRNAi00089666

• WormBase ID: WBRNAi00089666
• Genotype: oxEx229 [Mos1 Substrate, Pmyo-2::GFP]; oxEx166 [hsp::MosTransposase; unc-122::gfp; lin-15(+)]
• Phenotype Remark: met-2 RNAi increased the number of apoptosic bodies in gonads of animals treated with heat shock to induce Mos1 transposase-induced double stranded DNA breaks, as determined by Acridine Orange (AO) staining; met-2 RNAi also resulted in an accumulation of phosphorylated Chk1 (pChk1) protein in pachytene-stage germ lines, as determined by antibody staining
• Remark: (Figure 6A, 6B) met-2 RNAi

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Data Sets

• WormBaseAcedbConverter

1 Inhibits Gene

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00019883	met-2	R05D3.11	Caenorhabditis elegans

1 Inhibits Predicted Gene

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:R05D3.11	R05D3.11	3915	III: 8375300-8375395

0 Laboratories

3 Phenotype

Identifier	Name	Description
WBPhenotype:0001350	protein phosphorylation increased	Animals exhibit higher levels of protein phosphorylation compared to that observed in control animals.
WBPhenotype:0000183	apoptosis increased	Any perturbation that causes an elevation in the frequency of cell death by apoptosis compared to control animals.
WBPhenotype:0000426	antibody staining increased	Any variation that results in an increase in the characteristic expression of a gene product, as detected by antibody staining, compared to control animals.

0 Phenotype _ Not _ Observed

1 Reference

First Author	Title	Year	Journal	Volume	Pages	PubMed ID
						WBPaper00040176

0 Strain