WormMine

WS295

Intermine data mining platform for C. elegans and related nematodes

RNAi :

WormBase ID  WBRNAi00101802 Genotype  rrf-3(pk1426) II; ayIs6(hlh-8::gfp) X
Phenotype Remark  Postembryonic pop-1(RNAi) resulted in animals with both fewer sex myoblasts (SMs) derived from the M-lineage (in 41.4% of animals) as well extra sex myoblasts (SMs) derived from the M-lineage (in 9.1% of animals), as determined by hlh-8::GFP. Authors report that the loss of SMs was due to a fate transformation of M.v(l/r)pa to the fate of its posterior sister M.d(l/r)pp (normally fated to become body wall muscles (BWMs)). Remark  (Figure S4, Table 2) pop-1 RNAi-P (postembryonic RNAi). Exact sequence used for RNAi not stated by authors, Ahringer laboratory clone used for curation.

1 Organism

Name Taxon Id
Caenorhabditis elegans 6239

1 Data Sets

Name URL
WormBaseAcedbConverter  

1 Inhibits Gene

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00004077 pop-1 W10C8.2 Caenorhabditis elegans

1 Inhibits Predicted Gene

WormMine ID Sequence Name Length (nt) Chromosome Location
CDS:W10C8.2 W10C8.2 1317   I: 2823468-2823937

1 Laboratories

Primary Identifier
LW

5 Phenotype

Identifier Name Description
WBPhenotype:0000095 M lineage variant The descendants of the M precursor cell exhibit variations in developmental programs compared to their counterparts in control animals. In C. elegans the M lineage is a postembryonic mesodermal lineage.
WBPhenotype:0000961 pattern of transgene expression variant Any variation in the cellular or subcellular pattern of expression of a gene product produced by exogenous DNA that has been introduced into the organism compared to its expression in control animals.
WBPhenotype:0000414 cell fate transformation The cell takes on a different identity from which it was initially committed.
WBPhenotype:0002192 extra sex myoblasts Animals produce an excess number of sex myoblasts compared to controls.
WBPhenotype:0002191 fewer sex myoblasts Animals produce a reduced number of sex myoblasts compared to controls.

0 Phenotype _ Not _ Observed

1 Reference

First Author Title Year Journal Volume Pages PubMed ID
            WBPaper00033137

0 Strain