WormMine: RNAi WBRNAi00086201

• WormBase ID: WBRNAi00086201
• Phenotype Remark: Addition of 100 micromolar poly-unsaturated fatty acids (PUFAs) Eicosapentaenoic Acid and Di-homo-gamma-linolenic Acid to growth medium partially suppressed the phenotypes associated with mdt-15 RNAi: intestinal vacuoles, uncoordination, shortened lifespan, altered intestinal and germline morphology, and dead offspring

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Data Sets

• WormBaseAcedbConverter

1 Inhibits Gene

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00007016	mdt-15	R12B2.5	Caenorhabditis elegans

2 Inhibits Predicted Gene

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:R12B2.5b	R12B2.5b	2334	III: 5830222-5830320
CDS:R12B2.5a	R12B2.5a	2343	III: 5830222-5830320

1 Laboratories

Primary Identifier
KRY

6 Phenotype

Identifier	Name	Description
WBPhenotype:0000351	failure to hatch	Animals fail to emerge from an egg shell.
WBPhenotype:0000081	L1 arrest	The developmental program of the animals does not continue past the first larval stage (L1).
WBPhenotype:0000643	locomotion variant	Animals exhibit deviations in self-propelled movement on a solid medium compared to control animals.
WBPhenotype:0001428	intestinal vacuole	Vacuoles accumulate in the intestine.
WBPhenotype:0001171	shortened life span	The duration of viability in the adult phase of the life-cycle is less than that of control animals.
WBPhenotype:0000710	intestinal morphology variant	Animals exhibit variations in the form, structure or composition of the chain of cuboidal cells which form a central lumen lined by microvilli that allow the passage of food, compared to control. Food passes from the posterior pharynx to the intestine where it is digested and then on to the rectum which processes the waste products for excretion (Wormatlas).

0 Phenotype _ Not _ Observed

1 Reference

First Author	Title	Year	Journal	Volume	Pages	PubMed ID
						WBPaper00027365

0 Strain