WormMine

WS295

Intermine data mining platform for C. elegans and related nematodes

RNAi :

WormBase ID  WBRNAi00091303 Genotype  unc-119(ed3) III; cbgIs98[pPept-1:GFP::rab-11.1;unc-119(+)]
Phenotype Remark  cdc-42 RNAi suppressed (2.7-fold) the formation of ectopic, basolateral clusters of GFP::RAB-11 recycling endosomes and F-actin patches caused by par-5 RNAi Remark  (Figure 6b) M117.2/par-5, cdc-42/R07G3.1 double RNAi; Exact sequence used for cdc-42 RNAi not stated by authors, Ahringer laboratory clone used for curation.

1 Organism

Name Taxon Id
Caenorhabditis elegans 6239

1 Data Sets

Name URL
WormBaseAcedbConverter  

3 Inhibits Gene

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00000390 cdc-42 R07G3.1 Caenorhabditis elegans
WBGene00003920 par-5 M117.2 Caenorhabditis elegans
WBGene00010919 M117.3 M117.3 Caenorhabditis elegans

4 Inhibits Predicted Gene

WormMine ID Sequence Name Length (nt) Chromosome Location
CDS:R07G3.1 R07G3.1 576   II: 7616457-7616579
CDS:M117.2b M117.2b 381   IV: 11820991-11821284
CDS:M117.2a M117.2a 747   IV: 11820991-11821284
CDS:M117.3 M117.3 378   IV: 11823516-11823602

1 Laboratories

Primary Identifier
MZE

2 Phenotype

Identifier Name Description
WBPhenotype:0000679 transgene subcellular localization variant Any variation in the subcellular localization of a gene product produced by DNA coded for by exogenous genetic material that has been introduced into the organism compared to its expression in control animals.
WBPhenotype:0002107 RAB-11 recycling endosome localization variant Any variation in the subcellular localization of membrane bound organelles, known as recycling endosomes, positive for the RAB protein RAB-11, that traffic material from early endosomes back to the plasma membrane of the cell, thereby recycling recently endocytosed material to be reused at the plasma membrane.

0 Phenotype _ Not _ Observed

1 Reference

First Author Title Year Journal Volume Pages PubMed ID
            WBPaper00041129

0 Strain