WormMine: RNAi WBRNAi00094624

• WormBase ID: WBRNAi00094624
• Genotype: F35E12.5::GFP
• Phenotype Remark: aft-7 RNAi was able to reduce the expression of F35E12.5::GFP in animals that were exposed to RPW-24. RPW-24 was shown to increase the expression of the F35E12.5::GFP transcriptional reporter and to stimulate the host immune response. This effect was seen when animals were either grown on OP50 or infected P. aeruginosa PA14.
• Remark: RPW-24 is a molecule that protects C. elegans from bacterial infection by stimulating the host immune response. Addition of the small molecule RPW-24 was also shown to increase the expression of the F35E12.5::GFP transcriptional reporter. Exact sequence used for RNAi not stated by authors, spliced coding region sequence (07G2.2a) of gene used for curation.

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Data Sets

• WormBaseAcedbConverter

1 Inhibits Gene

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00000223	atf-7	C07G2.2	Caenorhabditis elegans

4 Inhibits Predicted Gene

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:C07G2.2a	C07G2.2a	1374	III: 4492306-4492416
CDS:C07G2.2c	C07G2.2c	1530	III: 4492306-4492416
CDS:C07G2.2b	C07G2.2b	1383	III: 4492306-4492416
CDS:C07G2.2d	C07G2.2d	1122	III: 4492786-4493101

1 Laboratories

Primary Identifier
AU

1 Phenotype

Identifier	Name	Description
WBPhenotype:0001278	transgene expression reduced	Any decrease in the intensity of expression of a gene product produced by exogenous DNA that has been introduced into the organism compared to its expression in control animals.

0 Phenotype _ Not _ Observed

1 Reference

First Author	Title	Year	Journal	Volume	Pages	PubMed ID
						WBPaper00041211

0 Strain