WormMine: RNAi WBRNAi00038556

• WormBase ID: WBRNAi00038556
• Remark: Over 90% of RNAi-treated embryos laid by worms fed for 48 h showed an early arrest, and no hatchlings were observed. The majority of embryos arrested between 8- and 32-cell stages. Adult worms that developed from embryos exposed to RNAi were completely sterile due to a failure in oocyte formation.

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Data Sets

• WormBaseAcedbConverter

1 Inhibits Gene

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00002000	hrpr-1	F58D5.1	Caenorhabditis elegans

2 Inhibits Predicted Gene

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:F58D5.1a	F58D5.1a	1836	I: 12060838-12060952
CDS:F58D5.1b	F58D5.1b	327	I: 12060838-12060952

0 Laboratories

3 Phenotype

Identifier	Name	Description
WBPhenotype:0000050	embryonic lethal	Animals die during embryonic development. In C. elegans, often assayed as refractile eggs that fail to hatch; when applied to large-scale RNAi screens in C. elegans, more than 10% of embryos die.
WBPhenotype:0000186	oogenesis variant	Any aberrancy in the processes that influence the generation and maturation of oocytes compared to control animals.
WBPhenotype:0000689	maternal sterile	Animals produce no or very few embryos as a result of experimental treatment. This is in contrast to sterility due to genetic perturbations (maternal effect sterility).

0 Phenotype _ Not _ Observed

1 Reference

First Author	Title	Year	Journal	Volume	Pages	PubMed ID
						WBPaper00024309

1 Strain

WormBase ID
WBStrain00000346