WormMine

WS295

Intermine data mining platform for C. elegans and related nematodes

RNAi :

WormBase ID  WBRNAi00091094 Genotype  unc-119(ed3) III; cbgIs91[pPept-1:pept-1::DsRed;unc-119(+)]; cbgIs98[pPept-1:GFP::rab-11.1;unc-119(+)]
Phenotype Remark  GFP::RAB-11 recycling endosome (RE) morphology appears diffuse or GFP::RAB-11 is cytosolically distributed; GFP::RAB-11 fluorescence intensity reduced; Autofluorescent lysosome-related organelles (AF/LROs) are enlarged or accumulated; Autofluorescent lysosome-related organelles (AF/LROs) appear diffuse Remark  (Table S1) K11D9.2/sca-1 RNAi
Paste the following link
Lists
This RNAi isn't in any lists. Upload a list.

1 Organism

Name Taxon Id
Caenorhabditis elegans 6239

1 Data Sets

Name URL
WormBaseAcedbConverter  

2 Inhibits Gene

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00004736 sca-1 K11D9.2 Caenorhabditis elegans
WBGene00194856 K11D9.5 K11D9.5 Caenorhabditis elegans

3 Inhibits Predicted Gene

WormMine ID Sequence Name Length (nt) Chromosome Location
CDS:K11D9.2c K11D9.2c 2799   III: 10812951-10813253
CDS:K11D9.2a K11D9.2a 3180   III: 10812951-10813253
CDS:K11D9.2b K11D9.2b 3015   III: 10812323-10812354

1 Laboratories

Primary Identifier
MZE

4 Phenotype

Identifier Name Description
WBPhenotype:0001278 transgene expression reduced Any decrease in the intensity of expression of a gene product produced by exogenous DNA that has been introduced into the organism compared to its expression in control animals.
WBPhenotype:0000679 transgene subcellular localization variant Any variation in the subcellular localization of a gene product produced by DNA coded for by exogenous genetic material that has been introduced into the organism compared to its expression in control animals.
WBPhenotype:0002094 RAB-11 recycling endosome morphology variant Any variation in the form or composition of membrane bound organelles, known as recycling endosomes, positive for the RAB protein RAB-11, that traffic material from early endosomes back to the plasma membrane of the cell, thereby recycling recently endocytosed material to be reused at the plasma membrane.
WBPhenotype:0002095 lysosome-related organelle morphology variant Any variation in the form or composition of membrane bound organelles, known as lysosome-related organelles (LROs) that, like lysosomes, have an acidic interior and generally act to digest components of the cell but are distinct in function, composition, and morphology, compared to control.

0 Phenotype _ Not _ Observed

1 Reference

First Author Title Year Journal Volume Pages PubMed ID
            WBPaper00041129

0 Strain