WormMine: RNAi WBRNAi00078094

• WormBase ID: WBRNAi00078094
• Genotype: rrf-3
• Phenotype Remark: Loss of precise DTC guidance along the DV axis of the lateral epidermis during the phase 2 migration. Authors call this the class-s (class-short) defect as it is caused by disruption of the mig-6 short isoform. Migration is not slow as seen with the disruption of the long isoform. In wildtype, phase 1 migration comprises a longitudinal migration in opposite directions away from the mid-body using the ventral body muscle basement membrane as a substratum for migration. During phase 2, the DTCs turn and migrate across the lateral epidermal basement membrane towards the dorsal body wall muscles.

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Data Sets

• WormBaseAcedbConverter

1 Inhibits Gene

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00003242	mig-6	C37C3.6	Caenorhabditis elegans

0 Inhibits Predicted Gene

1 Laboratories

Primary Identifier
NW

1 Phenotype

Identifier	Name	Description
WBPhenotype:0000195	distal tip cell migration variant	Variations in the migration pattern of distal tip cells compared to control animals. In C. elegans, DTCs located on the anterior and posterior ends of the gonad primordium typically migrate in a symmetrical U-shaped pattern.

2 Phenotype _ Not _ Observed

Identifier	Name	Description
WBPhenotype:0000749	embryonic development variant	Variations in the progression of an embryo over time, from zygote formation to hatching compared to control.
WBPhenotype:0000750	larval development variant	Variations in the progression of a larva over time, from its formation to the mature structure compared to control. The larva is the early, immature form of an animal between hatching and adulthood.

1 Reference

First Author	Title	Year	Journal	Volume	Pages	PubMed ID
						WBPaper00033006

0 Strain