WormMine: RNAi WBRNAi00110402

• WormBase ID: WBRNAi00110402
• Phenotype Remark: Knockdown of spg-7 by RNAi triggers the UPRmt response in C. elegans, by strong induction of the mitochondrial chaperone hsp-6 and of the proteases lonp-1 and clpp-1 as well as a reduction in ubl-5.

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Data Sets

• WormBaseAcedbConverter

1 Inhibits Gene

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00004978	spg-7	Y47G6A.10	Caenorhabditis elegans

1 Inhibits Predicted Gene

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:Y47G6A.10	Y47G6A.10	2349	I: 3467134-3467253

0 Laboratories

2 Phenotype

Identifier	Name	Description
WBPhenotype:0000717	gene expression variant	Variations in the processes that convert a gene's sequence into a mature gene product or products (proteins or RNA), compared to control.
WBPhenotype:0001719	unfolded protein response variant	Animals exhibit variations in any of the series of molecular signals generated as a consequence of the presence of unfolded proteins in the endoplasmic reticulum (ER) and or the mitochondria, compared to control. One such response is the increase in expression of chaperones.

0 Phenotype _ Not _ Observed

1 Reference

First Author	Title	Year	Journal	Volume	Pages	PubMed ID
						WBPaper00045732

1 Strain

WormBase ID
WBStrain00000001