WormMine

WS295

Intermine data mining platform for C. elegans and related nematodes

RNAi :

WormBase ID  WBRNAi00078133 Phenotype Remark  To analyze if nuclear protein import depends on NPP-19, authors determined the localization of GFP fused to either PCNA/PCN-1, a DNA replication co-factor, or PIE-1, an RNA polymerase II repressor essential for germ-line specification. Nuclear accumulation of GFP-PCN-1 was observed significantly earlier in control embryos than in npp-19(RNAi) embryos and reached higher concentrations. This data strongly suggests that nuclear protein import is impaired in the absence of NPP-19.

1 Organism

Name Taxon Id
Caenorhabditis elegans 6239

1 Data Sets

Name URL
WormBaseAcedbConverter  

1 Inhibits Gene

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00003805 npp-19 R06F6.5 Caenorhabditis elegans

2 Inhibits Predicted Gene

WormMine ID Sequence Name Length (nt) Chromosome Location
CDS:R06F6.5a R06F6.5a 1137   II: 10796894-10796965
CDS:R06F6.5b R06F6.5b 1146   II: 10796894-10796974

1 Laboratories

Primary Identifier
BN

1 Phenotype

Identifier Name Description
WBPhenotype:0001707 nuclear import defective The directed movement of substances into the nucleus is impaired.

0 Phenotype _ Not _ Observed

1 Reference

First Author Title Year Journal Volume Pages PubMed ID
            WBPaper00032497

0 Strain