WormMine: RNAi WBRNAi00077255

• WormBase ID: WBRNAi00077255
• Phenotype Remark: A GFP fusion with VPS-37 remained cytoplasmic in embryos co-depleted of TSG-101 and VPS-4, however simultaneous depletion of MVB-12 with VPS-4 failed to prevent the accumulation of GFP:VPS-37 on endosome membranes. Together, these data indicate that MVB-12 requires other ESCRT-I subunits for membrane association, but is itself dispensable for targeting of the remaining ESCRT-I subunits.

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Data Sets

• WormBaseAcedbConverter

2 Inhibits Gene

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00015508	mvb-12	C06A6.3	Caenorhabditis elegans
WBGene00021334	vps-4	Y34D9A.10	Caenorhabditis elegans

2 Inhibits Predicted Gene

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:Y34D9A.10	Y34D9A.10	1293	I: 1054362-1054469
CDS:C06A6.3	C06A6.3	834	IV: 7830573-7830677

1 Laboratories

Primary Identifier
OD

1 Phenotype

Identifier	Name	Description
WBPhenotype:0001421	endocytic transport variant	Animals exhibit variations in the directed movement of substances into, out of or mediated by the endosome, a membrane-bound organelle that trafficks material to different compartments of the cell or back to the plasma membrane for recycling compared to control.

0 Phenotype _ Not _ Observed

1 Reference

First Author	Title	Year	Journal	Volume	Pages	PubMed ID
						WBPaper00031035

1 Strain

WormBase ID
WBStrain00029229