WormMine

WS295

Intermine data mining platform for C. elegans and related nematodes

RNAi :

WormBase ID  WBRNAi00092769 Genotype  glp-1(e2141); H20-GFP [neuronal marker]
Phenotype Remark  glp-1(e2141);pop-1(RNAi) embryos had a much larger amount of hypodermal tissue than did glp-1(e2141) mutant embryos, but few if any neurons, as indicated by the lack of H20-GFP expression. The development of the first two AB daughters was analyzed individually in glp-1(e2141);pop-1(RNAi) embryos by killing all other blastomeres with a laser microbeam. Each AB daughter produced hypodermal cells almost exclusively. The lack of neurons in these experimental embryos indicates that pop-1(+) activity is required for the ABxxa fate. Remark  (Figure 4, Table 2) pop-1 RNAi. Exact sequence used for RNAi not stated by authors, spliced coding region sequence of gene used for curation.
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1 Organism

Name Taxon Id
Caenorhabditis elegans 6239

1 Data Sets

Name URL
WormBaseAcedbConverter  

1 Inhibits Gene

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00004077 pop-1 W10C8.2 Caenorhabditis elegans

1 Inhibits Predicted Gene

WormMine ID Sequence Name Length (nt) Chromosome Location
CDS:W10C8.2 W10C8.2 1317   I: 2823468-2823937

1 Laboratories

Primary Identifier
JJ

4 Phenotype

Identifier Name Description
WBPhenotype:0000097 AB lineage variant The descendants of the AB blastomere exhibit variations in developmental programs compared to their counterparts in control animals.
WBPhenotype:0001312 neuron number variant The quantity of neuronal cells, as a whole or of a specific class of neuron in the animal deviates from that observed in control animals.
WBPhenotype:0001643 excess hypodermal cells Embryos generate an excess number of hypodermal cells compared to control.
WBPhenotype:0008001 embryonic cell fate specification variant Any variation in the processes that govern acquisition of particular cell fates in the embryo, from the time of zygote formation until hatching compared to control.

0 Phenotype _ Not _ Observed

1 Reference

First Author Title Year Journal Volume Pages PubMed ID
            WBPaper00002998

0 Strain