WormMine: RNAi WBRNAi00007841

• WormBase ID: WBRNAi00007841
• Phenotype Remark: % penetrance range
• Remark: PCR product used to make dsRNA was amplified from genomic DNA.
• Secondary Identifier: PF:GL1_4A6

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Data Sets

• WormBaseAcedbConverter

1 Inhibits Gene

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00004874	smc-4	F35G12.8	Caenorhabditis elegans

1 Inhibits Predicted Gene

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:F35G12.8	F35G12.8	4650	III: 4587506-4587655

1 Laboratories

Primary Identifier
KK

13 Phenotype

Identifier	Name	Description
WBPhenotype:0000050	embryonic lethal	Animals die during embryonic development. In C. elegans, often assayed as refractile eggs that fail to hatch; when applied to large-scale RNAi screens in C. elegans, more than 10% of embryos die.
WBPhenotype:0000059	larval arrest	The developmental program of the animals halts at any larval stage and thus fails to reach adulthood. In C.elegans, this occurs anytime during L1-L4 stage.
WBPhenotype:0001106	spindle orientation variant AB or P1 early emb	The orientation of the spindle is aberrant in either the AB or the P1 cell.
WBPhenotype:0001155	pronuclei meet centrally early emb	The maternal and paternal pronuclei meet more centrally instead of meeting in the posterior end of the embryo.
WBPhenotype:0001143	multiple nuclei early emb	Embryos contain more than one nucleus per cell in the inviable one- to four-cell embryo.
WBPhenotype:0001130	cytokinesis fails early emb	Cells of the embryo attempt to divide but fail to form two daughter cells.
WBPhenotype:0002501	ectopic cleavage furrow early emb	One or more cells of the early embryo (one-cell stage to four-cell stage) exhibit one or more cleavage furrows in locations not normally found in control cells.
WBPhenotype:0001109	P0 spindle rotation delayed early emb	P0 spindle rotates late in the inviable one- to four-cell embryo.
WBPhenotype:0001141	nucleus reforms cell division remnant early emb	After division of either one-cell or two-cell embryos, the nuclei reappear next to the cell division remnant.
WBPhenotype:0001083	multiple cytoplasmic cavities early emb	Multiple vesicles, vacuoles, or cavities are seen during early embryogenesis.
WBPhenotype:0001134	Aba ABp division axis defective early emb	ABa or ABp divide in the wrong orientation.
WBPhenotype:0001124	ABa ABp EMS synchronous division early emb	EMS divides at the same time that ABa and ABp divide.
WBPhenotype:0001125	P2 EMS synchronous division early emb	P2 and EMS divide synchronously.

0 Phenotype _ Not _ Observed

1 Reference

First Author	Title	Year	Journal	Volume	Pages	PubMed ID
						WBPaper00005599

1 Strain

WormBase ID
WBStrain00000001