WormMine: RNAi WBRNAi00098020

• WormBase ID: WBRNAi00098020
• Genotype: sma-2(e502)
• Phenotype Remark: RNAi resulted in early and severe (shortening) effects on reproductive life span, increases the percentage of unhatched embryos in mated animals, and results in severely degraded germlines at day 8, in the sma-2(e502) mutant background.
• Remark: (Figure 6B, 6D, 6H, Table S1) smc-4 RNAi. Exact sequence used for RNAi not stated by authors, Ahringer laboratory clone used for curation.

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Data Sets

• WormBaseAcedbConverter

1 Inhibits Gene

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00004874	smc-4	F35G12.8	Caenorhabditis elegans

1 Inhibits Predicted Gene

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:F35G12.8	F35G12.8	4650	III: 4587506-4587655

1 Laboratories

Primary Identifier
CQ

3 Phenotype

Identifier	Name	Description
WBPhenotype:0000050	embryonic lethal	Animals die during embryonic development. In C. elegans, often assayed as refractile eggs that fail to hatch; when applied to large-scale RNAi screens in C. elegans, more than 10% of embryos die.
WBPhenotype:0001355	gonad morphology variant	Variations in the form or composition of a specialized tissue of the reproductive tract that produces the male or female gametes compared to control (Wormatlas).
WBPhenotype:0002169	reproductive longevity shortened	Animals stop producing progeny significantly before the time reproduction stops in control animals.

0 Phenotype _ Not _ Observed

1 Reference

First Author	Title	Year	Journal	Volume	Pages	PubMed ID
						WBPaper00037682

0 Strain