WormMine: RNAi WBRNAi00078678

• WormBase ID: WBRNAi00078678
• Genotype: hsp-4::gfp
• Phenotype Remark: Inactivation of ire-1 function by RNAi blocked both basal and inducible hsp-4::gfp expression in response to tunicamycin. Tunicamycin, in control animals, induces ER stress.

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Data Sets

• WormBaseAcedbConverter

1 Inhibits Gene

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00002147	ire-1	C41C4.4	Caenorhabditis elegans

2 Inhibits Predicted Gene

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:C41C4.4a	C41C4.4a	2904	II: 8112670-8112843
CDS:C41C4.4b	C41C4.4b	1878	II: 8112670-8112843

1 Laboratories

Primary Identifier
SJ

2 Phenotype

Identifier	Name	Description
WBPhenotype:0001719	unfolded protein response variant	Animals exhibit variations in any of the series of molecular signals generated as a consequence of the presence of unfolded proteins in the endoplasmic reticulum (ER) and or the mitochondria, compared to control. One such response is the increase in expression of chaperones.
WBPhenotype:0000359	tunicamycin response variant	Animals exhibit variations in the response to the addition of tunicamycin compared to that observed in control animals. Tunicamycin induces the unfolded protein response.

0 Phenotype _ Not _ Observed

1 Reference

First Author	Title	Year	Journal	Volume	Pages	PubMed ID
						WBPaper00005036

0 Strain