WormMine: RNAi WBRNAi00094500

• WormBase ID: WBRNAi00094500
• Genotype: dpy-5(e61); rrf-3(ok629)
• Phenotype Remark: RNAi resulted in suppression of the dumpy phenotype specifically of the dpy-5(e61) mutation carrying a premature termination codon, but not of the dpy-5(e907) null mutation, indicative of defective mRNA surveillance machinery
• Remark: (Figure 5N) smg-4 RNAi

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Data Sets

• WormBaseAcedbConverter

1 Inhibits Gene

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00004882	smg-4	F46B6.3	Caenorhabditis elegans

2 Inhibits Predicted Gene

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:F46B6.3b	F46B6.3b	1107	V: 9776193-9776324
CDS:F46B6.3a	F46B6.3a	990	V: 9776303-9776317

1 Laboratories

Primary Identifier
HZ

1 Phenotype

Identifier	Name	Description
WBPhenotype:0001538	mRNA surveillance defective	Defects in the cellular machinery that targets aberrant mRNAs species (nonsense codons, splice errors, altered untranslated regions etc.) for degradation. In C. elegans, mutations in such loci often act as allele-specific non gene-specific recessive suppressors of certain allele phenotypes and cause abnormal morphogenesis of male and hermaphrodite genitalia.

0 Phenotype _ Not _ Observed

1 Reference

First Author	Title	Year	Journal	Volume	Pages	PubMed ID
						WBPaper00040559

0 Strain