WormMine: RNAi WBRNAi00099039

• WormBase ID: WBRNAi00099039
• Genotype: elt-2::GFP
• Phenotype Remark: frk-1 RNAi arrested embryos contain extra gut nuclei. Furthermore, laser ablation of the E cell in early (six- to seven-cell stage) embryos eliminated all differentiated gut nuclei in both wild-type (9/9) and frk-1(RNAi).These results imply that the endoderm undergoes extra cell division in embryos lacking FRK-1, hence extra cell divisions are the cause of the extra cells, not incorrect specification.
• Remark: Exact sequence used for RNAi not stated by authors, spliced coding region sequence of gene used for curation. Method of delivery not explicit, authors say injection or soaking.

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Data Sets

• WormBaseAcedbConverter

1 Inhibits Gene

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00001487	frk-1	T04B2.2	Caenorhabditis elegans

1 Inhibits Predicted Gene

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:T04B2.2a	T04B2.2a	1173	IV: 10044263-10044564

1 Laboratories

Primary Identifier
JR

1 Phenotype

Identifier	Name	Description
WBPhenotype:0001636	excess intestinal cells	Animals contain an excess number of intestinal cells compared to control. In C. elegans, intestinal cells are derived from E-blastomere. The overproduction of intestinal tissues is a result of other blastomeres adopting an E-like fate or excess cell proliferation in the E lineage.

0 Phenotype _ Not _ Observed

1 Reference

First Author	Title	Year	Journal	Volume	Pages	PubMed ID
						WBPaper00037107

0 Strain