WormMine: RNAi WBRNAi00077718

• WormBase ID: WBRNAi00077718
• Genotype: Pmec-7::tat-1-IR; PhspANV::GFP
• Phenotype Remark: 13 to 19 percent of PLM neurons were missing, whereas in transgenic animals carrying the control vector few PLM neurons (3 to 4%) were lost. These results demonstrate that reduction of tat-1 activity may cause inappropriate phosphatidylserine exposure on the surface of somatic cells and the random loss of these cells.
• Remark: Exact sequence used for RNAi not stated by authors, Ahringer laboratory clone used for curation. Authors state that the tat-1 RNAi construct was made by polymerase chain reaction (PCR) amplification of 310 bp of the tat-1 coding region, but dont specify which portion.

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Data Sets

• WormBaseAcedbConverter

1 Inhibits Gene

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00013034	tat-1	Y49E10.11	Caenorhabditis elegans

3 Inhibits Predicted Gene

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:Y49E10.11a	Y49E10.11a	3420	III: 12399363-12399460
CDS:Y49E10.11c	Y49E10.11c	3579	III: 12401682-12402063
CDS:Y49E10.11b	Y49E10.11b	3270	III: 12404132-12404204

1 Laboratories

Primary Identifier
CU

2 Phenotype

Identifier	Name	Description
WBPhenotype:0001333	neuron cell body absent misplaced	The body of a neuron is not where it should be when compared to control animals; it is absent or misplaced.
WBPhenotype:0002178	plasma membrane leaflet composition variant	Any variation in the components that make up either of the two leaflets of the semipermeable bilayer surrounding a cell that separates the cell from its external environment compared to control.

0 Phenotype _ Not _ Observed

1 Reference

First Author	Title	Year	Journal	Volume	Pages	PubMed ID
						WBPaper00031830

0 Strain