WormMine

WS294

Intermine data mining platform for C. elegans and related nematodes

RNAi :

WormBase ID  WBRNAi00085473 Phenotype Remark  Apoptosis increased in in the germline.
Remark  Experiment SS158
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1 Organism

Name Taxon Id
Caenorhabditis elegans 6239

1 Data Sets

Name URL
WormBaseAcedbConverter  

1 Inhibits Gene

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00004459 rpn-2 C23G10.4 Caenorhabditis elegans

2 Inhibits Predicted Gene

WormMine ID Sequence Name Length (nt) Chromosome Location
CDS:C23G10.4a C23G10.4a 2616   III: 6199186-6199240
CDS:C23G10.4b C23G10.4b 2898   III: 6199186-6199240

1 Laboratories

Primary Identifier
OD

20 Phenotype

Identifier Name Description
WBPhenotype:0000688 sterile Animals generate defective gametes, are otherwise unable to reproduce or they generate progeny that are unable to reproduce.
WBPhenotype:0001355 gonad morphology variant Variations in the form or composition of a specialized tissue of the reproductive tract that produces the male or female gametes compared to control (Wormatlas).
WBPhenotype:0000183 apoptosis increased Any perturbation that causes an elevation in the frequency of cell death by apoptosis compared to control animals.
WBPhenotype:0001980 germ cell compartment expansion variant Animals exhibit variations in the increase in size of compartments of the germline. In the C. elegans germline, syncytial compartments enlarge just prior to and coincident with the loop region, eventually abscising, to become fully enclosed germ cells (oocytes).
WBPhenotype:0001180 accumulated germline cell corpses Animals exhibit an increase in the quantity of germ line cells that have undergone programmed cell death but have not been engulfed.
WBPhenotype:0001028 nuclear appearance variant The morphological appearance of nuclei differs from control animals.
WBPhenotype:0001982 cell membrane organization biogenesis variant Variations in the process(es) involved in the assembly, transport, arrangement or disassembly of cell membrane structures or components compared to control.
WBPhenotype:0001361 chromosome condensation variant Any variation in the progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division, or during apoptosis, in eukaryotic cells compared to control.
WBPhenotype:0000405 giant oocytes The size of haploid female germ cells (oocytes) are significantly larger compared to control.
WBPhenotype:0001940 rachis morphology variant Any variation in the form, structure or composition of the nucleus-free core of germ line cytoplasm in the gonad compared to control animals. In the C. elegans germline, nuclei exiting mitosis and entering meiosis are arranged along the cortex of the germline, partially enclosed by cellular membrane, forming a nucleus-free core of germline cytoplasm, called the rachis.
WBPhenotype:0001567 nuclei enlarged Nuclei of specific cells are larger compared to control animals.
WBPhenotype:0001948 diakinesis progression during oogenesis variant Developing oocytes show defects in their entry, progression through or exit from the diakinesis stage compared to control animals. Diakinesis is a cell cycle process comprising the steps by which a cell progresses through the final stage of prophase I in meiosis; the transition to meiotic metaphase I.
WBPhenotype:0001810 oocyte septum formation variant Animals exhibit variations in the partitioning of oocytes from each other compared to control animals.
WBPhenotype:0001971 germ cell compartment anucleate Germ cell compartments do not contain a nucleus.
WBPhenotype:0001969 germ cell compartment morphology variant Any variation in the form or composition of the compartments in the germline of females/hermaphrodites compared to control animals. In C. elegans these compartments contain a nucleus and are connected to a common cytoplasm (rachis). These compartments eventually undergo cellularization and become oocytes.
WBPhenotype:0001979 gonad vesiculated Animals contain small, fluid-filled, anucleate, spherical membrane-bound structures within the gonad.
WBPhenotype:0001950 diplotene region organization variant Animals exhibit variations from control animals in the organization of the germ cell nuclei in the gonad that are in the diplotene stage. In C. elegans the diplotene region follows the pachytene region and occurs just distal to, and coincident with, the loop in the gonad arm. In the diplotene region germ cell compartments become organized into a single file.
WBPhenotype:0001956 oocytes lack nucleus Haploid female germ cells (oocytes) lack a nucleus.
WBPhenotype:0001941 rachis narrow The nucleus-free core of germline cytoplasm in the gonad is not as wide as control animals.
WBPhenotype:0001942 rachis absent The nucleus-free core of germline cytoplasm in the gonad is missing.

0 Phenotype _ Not _ Observed

1 Reference

First Author Title Year Journal Volume Pages PubMed ID
            WBPaper00038381

1 Strain

WormBase ID
WBStrain00029219