WormMine

WS294

Intermine data mining platform for C. elegans and related nematodes

RNAi :

WormBase ID  WBRNAi00085380 Phenotype Remark 
Remark 

1 Organism

Name Taxon Id
Caenorhabditis elegans 6239

1 Data Sets

Name URL
WormBaseAcedbConverter  

2 Inhibits Gene

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00020275 atp-4 T05H4.12 Caenorhabditis elegans
WBGene00020274 T05H4.11 T05H4.11 Caenorhabditis elegans

1 Inhibits Predicted Gene

WormMine ID Sequence Name Length (nt) Chromosome Location
CDS:T05H4.12 T05H4.12 390   V: 6426396-6426542

1 Laboratories

Primary Identifier
OD

16 Phenotype

Identifier Name Description
WBPhenotype:0000688 sterile Animals generate defective gametes, are otherwise unable to reproduce or they generate progeny that are unable to reproduce.
WBPhenotype:0001260 oocyte morphology variant Haploid female germ cells (oocytes) exhibit variations in their overall structure, appearance or contents compared to control.
WBPhenotype:0000730 apoptosis variant Animals exhibit variations in any processes that influence the programmed cell death pathway. Induction of the apoptotic pathway triggers the activity of proteolytic caspases, which in turn lead to the destruction of the cell.
WBPhenotype:0001180 accumulated germline cell corpses Animals exhibit an increase in the quantity of germ line cells that have undergone programmed cell death but have not been engulfed.
WBPhenotype:0001952 germline nuclear positioning variant Variations in the directed movement/or positioning of a nucleus to a specific location within the germline compartment compared to control.
WBPhenotype:0001982 cell membrane organization biogenesis variant Variations in the process(es) involved in the assembly, transport, arrangement or disassembly of cell membrane structures or components compared to control.
WBPhenotype:0000405 giant oocytes The size of haploid female germ cells (oocytes) are significantly larger compared to control.
WBPhenotype:0001940 rachis morphology variant Any variation in the form, structure or composition of the nucleus-free core of germ line cytoplasm in the gonad compared to control animals. In the C. elegans germline, nuclei exiting mitosis and entering meiosis are arranged along the cortex of the germline, partially enclosed by cellular membrane, forming a nucleus-free core of germline cytoplasm, called the rachis.
WBPhenotype:0001948 diakinesis progression during oogenesis variant Developing oocytes show defects in their entry, progression through or exit from the diakinesis stage compared to control animals. Diakinesis is a cell cycle process comprising the steps by which a cell progresses through the final stage of prophase I in meiosis; the transition to meiotic metaphase I.
WBPhenotype:0001810 oocyte septum formation variant Animals exhibit variations in the partitioning of oocytes from each other compared to control animals.
WBPhenotype:0001971 germ cell compartment anucleate Germ cell compartments do not contain a nucleus.
WBPhenotype:0001969 germ cell compartment morphology variant Any variation in the form or composition of the compartments in the germline of females/hermaphrodites compared to control animals. In C. elegans these compartments contain a nucleus and are connected to a common cytoplasm (rachis). These compartments eventually undergo cellularization and become oocytes.
WBPhenotype:0001979 gonad vesiculated Animals contain small, fluid-filled, anucleate, spherical membrane-bound structures within the gonad.
WBPhenotype:0001950 diplotene region organization variant Animals exhibit variations from control animals in the organization of the germ cell nuclei in the gonad that are in the diplotene stage. In C. elegans the diplotene region follows the pachytene region and occurs just distal to, and coincident with, the loop in the gonad arm. In the diplotene region germ cell compartments become organized into a single file.
WBPhenotype:0001954 diplotene absent during oogenesis The diplotene stage is not observed in developing oocytes. Diplotene is a cell cycle process comprising the steps by which a cell progresses through the fourth stage of prophase I in meiosis, in which the homologous chromosomes begin to separate and the synaptonemal complex dissolves.
WBPhenotype:0001956 oocytes lack nucleus Haploid female germ cells (oocytes) lack a nucleus.

0 Phenotype _ Not _ Observed

1 Reference

First Author Title Year Journal Volume Pages PubMed ID
            WBPaper00038381

1 Strain

WormBase ID
WBStrain00029219