WormMine

WS294

Intermine data mining platform for C. elegans and related nematodes

RNAi :

WormBase ID  WBRNAi00090806 Genotype  unc-119(ed3) III; cbgIs91[pPept-1:pept-1::DsRed;unc-119(+)]; cbgIs98[pPept-1:GFP::rab-11.1;unc-119(+)]
Phenotype Remark  GFP::RAB-11 recycling endosome (RE) morphology appears diffuse or GFP::RAB-11 is cytosolically distributed; GFP::RAB-11 recycling endosomes (REs) accumulate within the cell; accumulations can be of different size, abundance, and sub-cellular localisation; GFP::RAB-11 fluorescence intensity reduced; Autofluorescent lysosome-related organelles (AF/LROs) are enlarged or accumulated Remark  (Table S1) ZK1151.1/vab-10 RNAi
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1 Organism

Name Taxon Id
Caenorhabditis elegans 6239

1 Data Sets

Name URL
WormBaseAcedbConverter  

1 Inhibits Gene

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00006876 vab-10 ZK1151.1 Caenorhabditis elegans

12 Inhibits Predicted Gene

WormMine ID Sequence Name Length (nt) Chromosome Location
CDS:ZK1151.1c ZK1151.1c 14832   I: 11747762-11747801
CDS:ZK1151.1m ZK1151.1m 14841   I: 11747762-11747801
CDS:ZK1151.1f ZK1151.1f 9933   I: 11764837-11770713
CDS:ZK1151.1e ZK1151.1e 9936   I: 11764837-11770713
CDS:ZK1151.1b ZK1151.1b 10716   I: 11764837-11770713
CDS:ZK1151.1a ZK1151.1a 11085   I: 11764837-11770713
CDS:ZK1151.1i ZK1151.1i 4494   I: 11773361-11773513
CDS:ZK1151.1d ZK1151.1d 10182   I: 11764837-11770713
CDS:ZK1151.1h ZK1151.1h 10275   I: 11764837-11770713
CDS:ZK1151.1j ZK1151.1j 14799   I: 11747762-11747801
CDS:ZK1151.1k ZK1151.1k 14460   I: 11747762-11747801
CDS:ZK1151.1l ZK1151.1l 15180   I: 11747762-11747801

1 Laboratories

Primary Identifier
MZE

4 Phenotype

Identifier Name Description
WBPhenotype:0000679 transgene subcellular localization variant Any variation in the subcellular localization of a gene product produced by DNA coded for by exogenous genetic material that has been introduced into the organism compared to its expression in control animals.
WBPhenotype:0001803 endosome biogenesis variant Animals exhibit variations in the formation or disassembly of membrane bound organelles that traffic material between the plasma membrane and internal compartments of the cell, compared to control.
WBPhenotype:0001430 lysosome organization biogenesis variant Variations in the processes that are carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lysosome, compared to control.
WBPhenotype:0002095 lysosome-related organelle morphology variant Any variation in the form or composition of membrane bound organelles, known as lysosome-related organelles (LROs) that, like lysosomes, have an acidic interior and generally act to digest components of the cell but are distinct in function, composition, and morphology, compared to control.

0 Phenotype _ Not _ Observed

1 Reference

First Author Title Year Journal Volume Pages PubMed ID
            WBPaper00041129

0 Strain