WormMine

WS294

Intermine data mining platform for C. elegans and related nematodes

RNAi :

WormBase ID  WBRNAi00090829 Genotype  unc-119(ed3) III; cbgIs91[pPept-1:pept-1::DsRed;unc-119(+)]; cbgIs98[pPept-1:GFP::rab-11.1;unc-119(+)]
Phenotype Remark  PEPT-1::DsRED fluorescence intensity reduced; GFP::RAB-11 recycling endosome (RE) morphology appears diffuse or GFP::RAB-11 is cytosolically distributed; GFP::RAB-11 recycling endosomes (REs) accumulate within the cell; accumulations can be of different size, abundance, and sub-cellular localisation; GFP::RAB-11 fluorescence intensity reduced Remark  (Table S1) F45F2.13/his-6 RNAi
Paste the following link
Lists
This RNAi isn't in any lists. Upload a list.

1 Organism

Name Taxon Id
Caenorhabditis elegans 6239

1 Data Sets

Name URL
WormBaseAcedbConverter  

6 Inhibits Gene

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00001876 his-2 T10C6.13 Caenorhabditis elegans
WBGene00001880 his-6 F45F2.13 Caenorhabditis elegans
WBGene00001891 his-17 K06C4.5 Caenorhabditis elegans
WBGene00001901 his-27 K06C4.13 Caenorhabditis elegans
WBGene00001914 his-40 K03A1.1 Caenorhabditis elegans
WBGene00001923 his-49 F07B7.5 Caenorhabditis elegans

6 Inhibits Predicted Gene

WormMine ID Sequence Name Length (nt) Chromosome Location
CDS:F07B7.5 F07B7.5 411   V: 8847943-8848353
CDS:K06C4.5 K06C4.5 411   V: 8897582-8897992
CDS:F45F2.13 F45F2.13 411   V: 8534567-8534977
CDS:K03A1.1 K03A1.1 411   X: 7310110-7310520
CDS:K06C4.13 K06C4.13 411   V: 8890038-8890448
CDS:T10C6.13 T10C6.13 411   V: 16041873-16042283

1 Laboratories

Primary Identifier
MZE

4 Phenotype

Identifier Name Description
WBPhenotype:0001278 transgene expression reduced Any decrease in the intensity of expression of a gene product produced by exogenous DNA that has been introduced into the organism compared to its expression in control animals.
WBPhenotype:0000679 transgene subcellular localization variant Any variation in the subcellular localization of a gene product produced by DNA coded for by exogenous genetic material that has been introduced into the organism compared to its expression in control animals.
WBPhenotype:0002094 RAB-11 recycling endosome morphology variant Any variation in the form or composition of membrane bound organelles, known as recycling endosomes, positive for the RAB protein RAB-11, that traffic material from early endosomes back to the plasma membrane of the cell, thereby recycling recently endocytosed material to be reused at the plasma membrane.
WBPhenotype:0002107 RAB-11 recycling endosome localization variant Any variation in the subcellular localization of membrane bound organelles, known as recycling endosomes, positive for the RAB protein RAB-11, that traffic material from early endosomes back to the plasma membrane of the cell, thereby recycling recently endocytosed material to be reused at the plasma membrane.

0 Phenotype _ Not _ Observed

1 Reference

First Author Title Year Journal Volume Pages PubMed ID
            WBPaper00041129

0 Strain