WormMine

WS294

Intermine data mining platform for C. elegans and related nematodes

RNAi :

WormBase ID  WBRNAi00091005 Genotype  unc-119(ed3) III; cbgIs91[pPept-1:pept-1::DsRed;unc-119(+)]; cbgIs98[pPept-1:GFP::rab-11.1;unc-119(+)]
Phenotype Remark  PEPT-1::DsRED accumulated in fuzzy or irregularly shaped structures; PEPT-1::DsRED fluorescence intensity reduced; GFP::RAB-11 recycling endosomes (REs) distribute evenly or scatter throughout the cell; GFP::RAB-11 recycling endosomes (REs) enrich apically, but with a different morphology or distribution than in wild type; Autofluorescent lysosome-related organelles (AF/LROs) appear diffuse Remark  (Table S1) T01D1.2/etr-1 RNAi
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1 Organism

Name Taxon Id
Caenorhabditis elegans 6239

1 Data Sets

Name URL
WormBaseAcedbConverter  

1 Inhibits Gene

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00001340 etr-1 T01D1.2 Caenorhabditis elegans

19 Inhibits Predicted Gene

WormMine ID Sequence Name Length (nt) Chromosome Location
CDS:T01D1.2e T01D1.2e 1761   II: 163142-163324
CDS:T01D1.2f T01D1.2f 1767   II: 163142-163324
CDS:T01D1.2g T01D1.2g 1542   II: 163142-163324
CDS:T01D1.2n T01D1.2n 1389   II: 164595-164643
CDS:T01D1.2o T01D1.2o 1170   II: 164595-164643
CDS:T01D1.2p T01D1.2p 1269   II: 164641-164643
CDS:T01D1.2r T01D1.2r 1044   II: 164641-164643
CDS:T01D1.2t T01D1.2t 1065   II: 166822-166905
CDS:T01D1.2w T01D1.2w 837   II: 167930-168047
CDS:T01D1.2a T01D1.2a 1755   II: 163142-163324
CDS:T01D1.2b T01D1.2b 1059   II: 166822-166905
CDS:T01D1.2d T01D1.2d 1608   II: 163142-163324
CDS:T01D1.2l T01D1.2l 1770   II: 163142-163324
CDS:T01D1.2m T01D1.2m 1395   II: 164595-164643
CDS:T01D1.2q T01D1.2q 1263   II: 164641-164643
CDS:T01D1.2s T01D1.2s 1071   II: 166822-166905
CDS:T01D1.2u T01D1.2u 846   II: 166822-166905
CDS:T01D1.2v T01D1.2v 843   II: 167930-168047
CDS:T01D1.2x T01D1.2x 618   II: 167930-168047

1 Laboratories

Primary Identifier
MZE

5 Phenotype

Identifier Name Description
WBPhenotype:0001278 transgene expression reduced Any decrease in the intensity of expression of a gene product produced by exogenous DNA that has been introduced into the organism compared to its expression in control animals.
WBPhenotype:0000679 transgene subcellular localization variant Any variation in the subcellular localization of a gene product produced by DNA coded for by exogenous genetic material that has been introduced into the organism compared to its expression in control animals.
WBPhenotype:0002094 RAB-11 recycling endosome morphology variant Any variation in the form or composition of membrane bound organelles, known as recycling endosomes, positive for the RAB protein RAB-11, that traffic material from early endosomes back to the plasma membrane of the cell, thereby recycling recently endocytosed material to be reused at the plasma membrane.
WBPhenotype:0002095 lysosome-related organelle morphology variant Any variation in the form or composition of membrane bound organelles, known as lysosome-related organelles (LROs) that, like lysosomes, have an acidic interior and generally act to digest components of the cell but are distinct in function, composition, and morphology, compared to control.
WBPhenotype:0002107 RAB-11 recycling endosome localization variant Any variation in the subcellular localization of membrane bound organelles, known as recycling endosomes, positive for the RAB protein RAB-11, that traffic material from early endosomes back to the plasma membrane of the cell, thereby recycling recently endocytosed material to be reused at the plasma membrane.

0 Phenotype _ Not _ Observed

1 Reference

First Author Title Year Journal Volume Pages PubMed ID
            WBPaper00041129

0 Strain