WormMine: RNAi WBRNAi00098299

• WormBase ID: WBRNAi00098299
• Genotype: let-60(n1046)
• Phenotype Remark: Using the let-60(n1046)/K-Ras gain of function allele, which increases the basal rate of apoptosis through the cytoplasmic stress pathway, misc-1 RNAi increased the apoptotic rate in an additive fashion (not synergistic). Author note this indicates that misc-1 does not function through this pathway.

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Data Sets

• WormBaseAcedbConverter

1 Inhibits Gene

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00015186	misc-1	B0432.4	Caenorhabditis elegans

1 Inhibits Predicted Gene

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:B0432.4	B0432.4	921	II: 286633-286691

1 Laboratories

Primary Identifier
DR

1 Phenotype

Identifier	Name	Description
WBPhenotype:0000730	apoptosis variant	Animals exhibit variations in any processes that influence the programmed cell death pathway. Induction of the apoptotic pathway triggers the activity of proteolytic caspases, which in turn lead to the destruction of the cell.

0 Phenotype _ Not _ Observed

1 Reference

First Author	Title	Year	Journal	Volume	Pages	PubMed ID
						WBPaper00038273

0 Strain