WormMine

WS294

Intermine data mining platform for C. elegans and related nematodes

RNAi :

WormBase ID  WBRNAi00112229 Genotype  vha-1p::gfp
Phenotype Remark  RNAi against ifb-1 in larvae led to the formation of cysts of variable size along the excretory canal or its complete collapse. Time-lapse analysis suggests that loss of canal integrity involved the disappearance of the entire structure, leaving a thin cytoplasmic thread lacking the lumen (Fig. 4d and Supplementary Video S8). Thus, the intermediate filament IFB-1 is essential to maintain apical membrane integrity. Remark  Exact sequence used for RNAi not stated by authors, Ahringer laboratory clone used for curation.
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1 Organism

Name Taxon Id
Caenorhabditis elegans 6239

1 Data Sets

Name URL
WormBaseAcedbConverter  

1 Inhibits Gene

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00002053 ifb-1 F10C1.2 Caenorhabditis elegans

2 Inhibits Predicted Gene

WormMine ID Sequence Name Length (nt) Chromosome Location
CDS:F10C1.2b F10C1.2b 1770   II: 5765642-5765774
CDS:F10C1.2a F10C1.2a 1677   II: 5768961-5769000

0 Laboratories

1 Phenotype

Identifier Name Description
WBPhenotype:0000704 excretory canal morphology variant Variations in the form or composition of structures made by the processes of the excretory canal cell compared to control (Wormatlas).

0 Phenotype _ Not _ Observed

1 Reference

First Author Title Year Journal Volume Pages PubMed ID
            WBPaper00041965

0 Strain