WormMine: RNAi WBRNAi00108790

• WormBase ID: WBRNAi00108790
• Genotype: dvIs70 [hsp-16.2::GFP]
• Phenotype Remark: "To assess whether the reduced abundance of free amino acids alters protein synthesis, we quantified the synthesis of GFP controlled by the hsp-16.2 promoter. Cycloheximide, as an inhibitor of protein synthesis, diminished the apparent GFP synthesis rate by ~30%. When pept-1 was downregulated by RNAi, the GFP synthesis rate was reduced to around 50% relative to that in wild-type animals (Figure 4B). These findings indicate that the reduced amino acid availability in pept-1 is associated with a significantly reduced de novo protein synthesis."
• Remark: (Figure 4B) pept-1 RNAi

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Data Sets

• WormBaseAcedbConverter

1 Inhibits Gene

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00003877	pept-1	K04E7.2	Caenorhabditis elegans

1 Inhibits Predicted Gene

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:K04E7.2	K04E7.2	2508	X: 6457033-6457075

0 Laboratories

1 Phenotype

Identifier	Name	Description
WBPhenotype:0000120	protein expression reduced	Any change that results in lower than normal levels of protein expression compared to control animals.

0 Phenotype _ Not _ Observed

1 Reference

First Author	Title	Year	Journal	Volume	Pages	PubMed ID
						WBPaper00045460

1 Strain

WormBase ID
WBStrain00005096