WormMine: RNAi WBRNAi00087867

• WormBase ID: WBRNAi00087867
• Phenotype Remark: Extra iron decreased normal lifespan, but exposure to unc-62 RNAi restored normal lifespan. In addition iron chelation had no influence on normal lifespan but prevented the longevity enhancing effects of unc-62 RNAi.These experiments suggest that iron availability is essential to UNC-62 suppression-mediated longevity phenotypes and indicates that UNC-62 is involved in iron metabolism.
• Remark: Exact sequence used for RNAi not stated by authors, spliced coding region sequence of gene used for curation (T28F12.2a.1).

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Data Sets

• WormBaseAcedbConverter

1 Inhibits Gene

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00006796	unc-62	T28F12.2	Caenorhabditis elegans

8 Inhibits Predicted Gene

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:T28F12.2a	T28F12.2a	1695	V: 4497467-4497589
CDS:T28F12.2f	T28F12.2f	1683	V: 4497467-4497589
CDS:T28F12.2b	T28F12.2b	1584	V: 4499796-4499807
CDS:T28F12.2e	T28F12.2e	1572	V: 4499796-4499807
CDS:T28F12.2g	T28F12.2g	1473	V: 4501318-4501400
CDS:T28F12.2d	T28F12.2d	336	V: 4509913-4510148
CDS:T28F12.2c	T28F12.2c	462	V: 4505814-4505905
CDS:T28F12.2h	T28F12.2h	1461	V: 4501318-4501400

0 Laboratories

1 Phenotype

Identifier	Name	Description
WBPhenotype:0002046	iron homeostasis variant	Variations in the regulation of levels, transport, and metabolism of iron within an organism compared to control.

0 Phenotype _ Not _ Observed

1 Reference

First Author	Title	Year	Journal	Volume	Pages	PubMed ID
						WBPaper00039832

0 Strain