WormMine: Gene WBGene00019347

• WormBase Gene ID: WBGene00019347
• Gene Name: mbl-1
• Sequence Name: K02H8.1
• Brief Description: mbl-1 encodes, by alternative splicing, two isoforms of a putative MUSCLEBLIND-type mRNA splicing regulator required in adults for normal muscle dense body organization, locomotion, and vulval morphogenesis; MBL-1 is orthologous to Drosophila MBL and human MBNL1 (OMIM:606516), MBNL2 (OMIM:607327), and MBNL3 (OMIM:300413); mbl-1 is transcribed in larvae and adults; mbl-1(RNAi) animals show protruding vulvae, progressive uncoordination, and disordered dense bodies; while mbl-1 is required in adults, it is dispensable in larvae, perhaps reflecting a progressive muscle dystrophy in mbl-1(RNAi) animals.
• Organism: Caenorhabditis elegans
• Automated Description: Predicted to enable RNA binding activity. Predicted to be involved in regulation of RNA splicing. Predicted to be located in cytoplasm and nucleoplasm. Expressed in several structures, including excretory cell and tail. Used to study myotonic disease. Human ortholog(s) of this gene implicated in schizophrenia. Is an ortholog of human MBNL3 (muscleblind like splicing regulator 3).
• Biotype: SO:0001217
• Genetic Position: X :24.0691 ±0.001044
• Length (nt): 31695

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Synonyms

• Value: WBGene00019347

Genomics

10 Transcripts

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
Transcript:K02H8.1d.1	K02H8.1d.1	2639	X: 16978608-17010300
Transcript:K02H8.1e.1	K02H8.1e.1	2400	X: 16978608-17010286
Transcript:K02H8.1c.2	K02H8.1c.2	2895	X: 16986539-17010302
Transcript:K02H8.1a.1	K02H8.1a.1	1143	X: 16986629-17008361
Transcript:K02H8.1f.1	K02H8.1f.1	1089	X: 16986629-17008786
Transcript:K02H8.1g.1	K02H8.1g.1	855	X: 16986638-17008786
Transcript:K02H8.1c.3	K02H8.1c.3	2761	X: 16989549-17010302
Transcript:K02H8.1a.2	K02H8.1a.2	978	X: 17001728-17008361
Transcript:K02H8.1b.1	K02H8.1b.1	1023	X: 17001730-17008462
Transcript:K02H8.1c.1	K02H8.1c.1	2636	X: 17001730-17010300

Other

7 CDSs

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:K02H8.1f	K02H8.1f	1080	X: 16986638-16986679
CDS:K02H8.1g	K02H8.1g	855	X: 16986638-16986679
CDS:K02H8.1a	K02H8.1a	975	X: 17001731-17001850
CDS:K02H8.1b	K02H8.1b	921	X: 17001731-17001850
CDS:K02H8.1c	K02H8.1c	696	X: 17001731-17001850
CDS:K02H8.1d	K02H8.1d	1125	X: 16978608-16978694
CDS:K02H8.1e	K02H8.1e	900	X: 16978608-16978694

1 RNAi Result

• WBRNAi00049779

486 Allele

• gk964260
• gk962707
• gk963810
• gk963581
• otn10533
• otn10534
• gk833719
• tm12948
• gk530017
• WBVar01554677
• gk749338
• gk859395
• tm11421
• otn12733
• WBVar01691505
• WBVar01929579
• WBVar01929578
• WBVar01929580
• WBVar01929582
• WBVar01929581
• WBVar01929584
• WBVar01929583
• WBVar01929586
• WBVar01929585
• WBVar01693759
• WBVar01820599
• gk307017
• WBVar01680229
• gk556428
• WBVar00245410

1 Chromosome

• WormBase ID: X
• Organism: Caenorhabditis elegans
• Length (nt): 17718942

1 Chromosome Location

• Feature . Primary Identifier: WBGene00019347
• Start: 16978608
• End: 17010302
• Strand: 1

4 Data Sets

• WormBaseAcedbConverter
• GO Annotation data set
• C. elegans genomic annotations (GFF3 Gene)
• Panther orthologue and paralogue predictions

1 Downstream Intergenic Region

• WormBase ID: intergenic_region_chrX_17010303..17013461
• Length (nt): 3159
• Chromosome Location: X: 17010303-17013461
• Organism: Caenorhabditis elegans

151 Expression Clusters

Regulated By Treatment	Description	Algorithm	Primary Identifier
	Transcripts that showed significantly increased expression in L1 neural cells comparing to in adult neural cells.	DESeq2 (v1.18.1) fold change > 2, P-adj<0.05, using BenjaminiHochberg correction.	WBPaper00060811:L1_vs_adult_upregulated_neural
	Transcripts of coding genes that showed significantly decreased expression in muscle.	DESeq2 (version 1.24.0). Transcripts with a false-discovery rate adjusted p-value less than 0.05 were considered significantly differentially expressed.	WBPaper00062325:muscle_depleted_coding-RNA
	Transcripts expressed in neuronal cells, by analyzingfluorescence-activated cell sorted (FACS) neurons.	DESeq. False discovry rate (FDR) < 0.1.	WBPaper00048988:neuron_expressed
	Genes significantly enriched (> 2x, FDR < 5%) in a particular cell-type versus a reference sample of all cells at the same stage.	A Mann-Whitney U test with an empirical background model and FDR correction for multiple testing was used to detect expressed transcripts (Benjamini and Hochberg 1995). Genes and TARs with an FDR <= 0.05 were reported as expressed above background. Authors detected differentially expressed transcripts using a method based on linear models. Genes and TARs were called differentially expressed if the FDR was <= 0.05 and the fold change (FC) >= 2.0. To more strictly correct for potential false-positives resulting from multiple sample comparisons, authors divided individual FDR estimates by the number of samplesor sample comparisons, respectively. This resulted in an adjusted FDR of 1.3 * 0.0001 for expression above background and of 7.4 * 0.0001 for differential expression. Authors called genes selectively enriched in a given tissue if they met the following requirements: (1) enriched expression in a given tissue (FDR <= 0.05 and FC >= 2.0), (2) fold change versus reference among the upper 40% of the positive FC range observed for this gene across all tissues, and (3) fold-change entropy among the lower 40% of the distribution observed for all genes.	WBPaper00037950:A-class-motor-neurons_larva_enriched
adult vs dauer larva	Transcripts that showed differential expression in adult vs dauer lava in N2 animals at 20C.	N.A.	WBPaper00050488:adult_vs_dauer_regulated_N2_20C
	Neuronally enriched transcripts according to a comparison of neuronal nuclei IP samples to total nuclei using isolation of nuclei from tagged specific cell types (INTACT) technology.	DESEQ2, fold change > 2 and FDR < 0.01.	WBPaper00062103:neuron_enriched
	Transcripts that showed significantly increased expression glp-1(e2141); TU3401 animals comparing to in TU3401 animals.	Fold change > 2, FDR < 0.01.	WBPaper00065993:glp-1(e2141)_upregulated
	Transcripts expressed in the epithelial tissues surrounding the pharynx that includes the arcade and intestinal valve (AIV) cells, according to PAT-Seq analysis using Pbath-15-GFP-3XFLAG mRNA tagging.	Cufflinks FPKM value >=1.	WBPaper00050990:arcade_intestinal-valve_expressed
	Transcripts expressed in body muscle, according to PAT-Seq analysis using Pmyo-3-GFP-3XFLAG mRNA tagging.	Cufflinks FPKM value >=1.	WBPaper00050990:body-muscle_expressed
	Transcripts expressed in GABAergic neuron, according to PAT-Seq analysis using Punc-47-GFP-3XFLAG mRNA tagging.	Cufflinks FPKM value >=1.	WBPaper00050990:GABAergic-neuron_expressed
	Transcripts expressed in intestine, according to PAT-Seq analysis using Pges-1-GFP-3XFLAG mRNA tagging.	Cufflinks FPKM value >=1.	WBPaper00050990:intestine_expressed
	Transcripts expressed in NMDA neuron, according to PAT-Seq analysis using Pnmr-1-GFP-3XFLAG mRNA tagging.	Cufflinks FPKM value >=1.	WBPaper00050990:NMDA-neuron_expressed
	Transcripts expressed in pharynx, according to PAT-Seq analysis using Pmyo-2-GFP-3XFLAG mRNA tagging.	Cufflinks FPKM value >=1.	WBPaper00050990:pharynx_expressed
	Transcripts that showed significantly increased expression after four-day-old young adult worms were placed on NGM plates seeded with OP50 in the presence 5% Agaro-oligosaccharides(AGO) for 24 h, comparing to animals grown in the absence of AGO.	Fold change > 2.	WBPaper00064306:Agaro-oligosaccharides_upregulated
	Transcripts that showed significantly increased expression in sin-3(tm1276) comparing to in N2.	DESeq2, fold change > 2, p-value < 0.01.	WBPaper00061203:sin-3(tm1276)_upregulated
	Genes that showed significantly increased expression in daf-2(e1370) comparing to in N2.	To identify DEGs, Students t test and the log2 median ratio test were performed to compute t values and median ratios for all the annotated genes. The adjusted P values from each test were computed using an empirical distribution of the null hypothesis, which was obtained from random permutations of the samples. Finally, the adjusted P values from the individual tests were combined to compute the overall P values using Stouffers method , and genes with overall P < 0.05 and fold change > 1.5 were selected as DEGs.	WBPaper00047131:daf-2(e1370)_upregulated_N2-background
	Transcripts that showed significantly decreased expression in N2 animals exposed to 0.1mM Paraquat from hatching to reaching adult stage.	DESeq2 version 1.22.2, p < 0.05	WBPaper00064716:paraquat_downregulated
	Transcripts that showed significantly changed expression in 6-day post-L4 adult hermaphrodite comparing to in 1-day post L4 adult hermaphrodite animals.	Sleuth	WBPaper00051558:aging_regulated
	Transcripts that showed significantly altered expression after 24 hour exposure to stavudine (d4T) starting at L1 lava stage.	DESeq	WBPaper00053302:stavudine_24h_regulated
	Transcripts that showed significantly decreased expression in sin-3(tm1276) comparing to in N2 at early embryo when there were only 3 -5 eggs in the adult.	DESeq2, fold change > 2, adjusted p-value < 0.01	WBPaper00058598:sin-3(tm1276)_downregulated
	Transcripts depleted in purified oocyte P bodies comparing to in the whole animal.	DESeq2, FDR < 0.05, fold change > 2.	WBPaper00065975:P-body_vs_WholeAnimal_depleted
	Transcripts detected in body muscle nuclei according to a nuclear FACS-based strategy.	Cufflinks	WBPaper00065120:body-muscle-transcriptome
	Genes that showed expression levels higher than the corresponding reference sample (L2 all cell reference).	A Mann-Whitney U test with an empirical background model and FDR correction for multiple testing was used to detect expressed transcripts (Benjamini and Hochberg 1995). Genes and TARs with an FDR <= 0.05 were reported as expressed above background. Authors detected differentially expressed transcripts using a method based on linear models. Genes and TARs were called differentially expressed if the FDR was <= 0.05 and the fold change (FC) >= 2.0. To more strictly correct for potential false-positives resulting from multiple sample comparisons, authors divided individual FDR estimates by the number of samplesor sample comparisons, respectively. This resulted in an adjusted FDR of 1.3 * 0.0001 for expression above background and of 7.4 * 0.0001 for differential expression. Authors called genes selectively enriched in a given tissue if they met the following requirements: (1) enriched expression in a given tissue (FDR <= 0.05 and FC >= 2.0), (2) fold change versus reference among the upper 40% of the positive FC range observed for this gene across all tissues, and (3) fold-change entropy among the lower 40% of the distribution observed for all genes.	WBPaper00037950:A-class-motor-neurons_L2-larva_expressed
	Genes that showed expression levels higher than the corresponding reference sample (L2 all cell reference).	A Mann-Whitney U test with an empirical background model and FDR correction for multiple testing was used to detect expressed transcripts (Benjamini and Hochberg 1995). Genes and TARs with an FDR <= 0.05 were reported as expressed above background. Authors detected differentially expressed transcripts using a method based on linear models. Genes and TARs were called differentially expressed if the FDR was <= 0.05 and the fold change (FC) >= 2.0. To more strictly correct for potential false-positives resulting from multiple sample comparisons, authors divided individual FDR estimates by the number of samplesor sample comparisons, respectively. This resulted in an adjusted FDR of 1.3 * 0.0001 for expression above background and of 7.4 * 0.0001 for differential expression. Authors called genes selectively enriched in a given tissue if they met the following requirements: (1) enriched expression in a given tissue (FDR <= 0.05 and FC >= 2.0), (2) fold change versus reference among the upper 40% of the positive FC range observed for this gene across all tissues, and (3) fold-change entropy among the lower 40% of the distribution observed for all genes.	WBPaper00037950:all-neurons_L2-larva_expressed
	Transcripts that showed significantly increased expression in animals with germline-specific inx-14(RNAi) comparing to in aniamls fed with control vector, both exposed to PA14 infection.	DESeq2. Differentially-expressed genes (DEG) were identified based on two criteria: FDR (False discovery rateusing Benjamini-Hochberg adjusted p-values) < 0.01 and absolute value of log2(Fold Change) > 1.	WBPaper00066146:germline-inx-14(RNAi)_upregulated_PA14
	Transcripts that showed significantly decreased expression in miR-85(n4117), comparing to in N2 at 20C.	DESeq2 FDR < 0.05	WBPaper00061800:miR-85(n4117)_downregulated_20C
	Transcripts that showed significantly increased expression in hda-1(ne4752[3xFLAG-Degron-HDA-1]) in gonads dissected from 1-day old adult animals.	Salmon was used to map the mRNA-seq reads with the worm database WS268, and its output files were imported to DESeq2 in R. The differentially expressed genes were filtered by fold change more than 2 and adjusted p-value < 0.05. The scatter plots were generated by the plot function in R.	WBPaper00061479:hda-1(ne4752)_upregulated
	Genes that showed expression levels higher than the corresponding reference sample (L3/L4 all cell reference).	A Mann-Whitney U test with an empirical background model and FDR correction for multiple testing was used to detect expressed transcripts (Benjamini and Hochberg 1995). Genes and TARs with an FDR <= 0.05 were reported as expressed above background. Authors detected differentially expressed transcripts using a method based on linear models. Genes and TARs were called differentially expressed if the FDR was <= 0.05 and the fold change (FC) >= 2.0. To more strictly correct for potential false-positives resulting from multiple sample comparisons, authors divided individual FDR estimates by the number of samplesor sample comparisons, respectively. This resulted in an adjusted FDR of 1.3 * 0.0001 for expression above background and of 7.4 * 0.0001 for differential expression. Authors called genes selectively enriched in a given tissue if they met the following requirements: (1) enriched expression in a given tissue (FDR <= 0.05 and FC >= 2.0), (2) fold change versus reference among the upper 40% of the positive FC range observed for this gene across all tissues, and (3) fold-change entropy among the lower 40% of the distribution observed for all genes.	WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
	Transcripts that showed significantly increased expression in mep-1(ne4629[MEP-1-GFP-Degron]) in gonads dissected from 1-day old adult animals.	Salmon was used to map the mRNA-seq reads with the worm database WS268, and its output files were imported to DESeq2 in R. The differentially expressed genes were filtered by fold change more than 2 and adjusted p-value < 0.05. The scatter plots were generated by the plot function in R.	WBPaper00061479:mep-1(ne4629)_upregulated
	Genes that showed expression levels higher than the corresponding reference sample (L2 all cell reference).	A Mann-Whitney U test with an empirical background model and FDR correction for multiple testing was used to detect expressed transcripts (Benjamini and Hochberg 1995). Genes and TARs with an FDR <= 0.05 were reported as expressed above background. Authors detected differentially expressed transcripts using a method based on linear models. Genes and TARs were called differentially expressed if the FDR was <= 0.05 and the fold change (FC) >= 2.0. To more strictly correct for potential false-positives resulting from multiple sample comparisons, authors divided individual FDR estimates by the number of samplesor sample comparisons, respectively. This resulted in an adjusted FDR of 1.3 * 0.0001 for expression above background and of 7.4 * 0.0001 for differential expression. Authors called genes selectively enriched in a given tissue if they met the following requirements: (1) enriched expression in a given tissue (FDR <= 0.05 and FC >= 2.0), (2) fold change versus reference among the upper 40% of the positive FC range observed for this gene across all tissues, and (3) fold-change entropy among the lower 40% of the distribution observed for all genes.	WBPaper00037950:excretory-cell_L2-larva_expressed

14 Expression Patterns

• Primary Identifier: Expr12223
• Pattern: mbl-1 is expressed mostly or exclusively in neurons including the PVD.

• Primary Identifier: Expr14692
• Pattern: A fosmid reporter for mbl-1 exhibits expression in the ALM neuron, as well as many other neurons in the nervous system. This is in line with previous reports on mbl-1 expression (Spilker et al., 2012). MBL-1, visualized by a translational RFP fusion is expressed specifically in the excitatory cholinergic neurons of the ventral nerve cord, visualized by an unc-17::BFP promoter reporter.

• Primary Identifier: Expr16427
• Pattern: To examine the localization pattern of MBL-1, we used an MBL-1::GFP translational reporter under its native promoter and observed GFP expression in several tissues throughout the body of the animal. MBL-1::GFP was highly enriched in ALM and PLM neurons, with localization detected in the cell bodies as well as in the PLM and ALM neurites.

• Primary Identifier: Expr8967
• Remark: Picture: Fig. 8.
• Pattern: Analysis of GFP expression in the nematodes showed fluorescence in the excretory cell, seminal vesicle, and nerve cells that run parallel to the pharynx and body axis. GFP expression was observed at all developmental stages, including egg, L1L4, and adult.

• Primary Identifier: Expr9938
• Pattern: mbl-1 promoter drives expression of mCherry in many cell bodies along the ventral nerve cord. Thin neuronal processes emanate from these cell bodies and fasciculate in both the dorsal and ventral nerve cords. MBL-1 is expressed strongly in all of the A-type motorneurons, and also in other neurons in the ventral cord and several unidentified cells in the tail. mCherry expression was seen in embryonic and L1 animals, indicating that mbl-1 is expressed early in development.
• Subcellular Localization: MBL- 1::GFP is concentrated in the nucleus of ventral cord neurons.

• Primary Identifier: Expr16535
• Pattern: Long isoform. We generated strains that express either long(ex7+) or short(ex7-) MBL-1 protein isoforms, tagged with mCherry, under both endogenous promoters together, and investigated their subcellular localization at the L4 larval stage (when most tissue development is complete). Expression of MBL-1 was detected in various tissues in a pattern consistent with previous studies [38, 39], specifically in the head and tail ganglia, the ventral nerve cord (VNC), the spermatheca, and the posterior gut. Consistent with the human longer MBNL isoform, mCherry signals showed a distinct nuclear localization when linked with long(ex7+) isoforms, most noticeably in, but not limited to, cells of the gut and the head region. In contrast, short(ex7-) isoforms showed a more diffuse pattern, consistent with localization both in the nucleus and cytoplasm. We note that the expression in the gut might be ectopic and a possible consequence of the presence of the unc-54 30-UTR, as reported before [43].

• Primary Identifier: Expr16536
• Pattern: Short isoform. We generated strains that express either long(ex7+) or short(ex7-) MBL-1 protein isoforms, tagged with mCherry, under both endogenous promoters together, and investigated their subcellular localization at the L4 larval stage (when most tissue development is complete). Expression of MBL-1 was detected in various tissues in a pattern consistent with previous studies [38, 39], specifically in the head and tail ganglia, the ventral nerve cord (VNC), the spermatheca, and the posterior gut. Consistent with the human longer MBNL isoform, mCherry signals showed a distinct nuclear localization when linked with long(ex7+) isoforms, most noticeably in, but not limited to, cells of the gut and the head region. In contrast, short(ex7-) isoforms showed a more diffuse pattern, consistent with localization both in the nucleus and cytoplasm. We note that the expression in the gut might be ectopic and a possible consequence of the presence of the unc-54 30-UTR, as reported before [43].

• Primary Identifier: Expr1153494
• Pattern: Developmental gene expression time-course. Raw data can be downloaded from ftp://caltech.wormbase.org/pub/wormbase/datasets-published/hashimshony2015

• Primary Identifier: Expr12226
• Subcellular Localization: MBL-1 translation fusion to GFP shows clear nuclear expression.

• Primary Identifier: Expr1038361
• Pattern: Tiling arrays expression graphs

• Primary Identifier: Expr2013433
• Pattern: Single cell embryonic expression. Only cell types with an expression fraction of greater 0.2 of the maximum expressed fraction are labeled (Full data can be downloaded from http://caltech.wormbase.org/pub/wormbase/datasets-published/packer2019/). The colors represent the broad cell class to which the cell type has been assigned. The size of the point is proportional to the log2 of the numbers of cells in the dataset of that cell type. Interactive visualizations are available as a web app (https://cello.shinyapps.io/celegans/) and can also be installed as an R package (https://github.com/qinzhu/VisCello.celegans).

• Primary Identifier: Expr1012701
• Pattern: Developmental gene expression time-course. Raw data can be downloaded from ftp://caltech.wormbase.org/pub/wormbase/datasets-published/levin2012

• Primary Identifier: Expr15780
• Pattern: Two alternatively spliced isoforms, CeMbl-a and CeMbl-b, were identified. Both isoforms are expressed in larval and adult stages.

• Primary Identifier: Expr2031667
• Pattern: Single cell embryonic expression. Only cell types with an expression fraction of greater 0.2 of the maximum expressed fraction are labeled (Full data can be downloaded from http://caltech.wormbase.org/pub/wormbase/datasets-published/packer2019/). The colors represent the broad cell class to which the cell type has been assigned. The size of the point is proportional to the log2 of the numbers of cells in the dataset of that cell type. Interactive visualizations are available as a web app (https://cello.shinyapps.io/celegans/) and can also be installed as an R package (https://github.com/qinzhu/VisCello.celegans).

10 GO Annotation

11 Homologues

1 Locations

• Feature . Primary Identifier: WBGene00019347
• Start: 16978608
• End: 17010302
• Strand: 1

10 Ontology Annotations

12 Regulates Expr Cluster

Regulated By Treatment	Description	Algorithm	Primary Identifier
	Transcripts that showed significantly increased expression in mbl-1(syb4318), referred to as mbl-1short(ex7-), comparing to in N2 at L4 larva stage.	DESeq2, Fold change > 2 and FDR < 0.05	WBPaper00066410:mbl-1(syb4318)_upregulated
	Transcripts that showed significantly increased expression in mbl-1(syb4345), referred to as mbl-1long(ex7+), comparing to in N2 at L4 larva stage.	DESeq2, Fold change > 2 and FDR < 0.05	WBPaper00066410:mbl-1(syb4345)_upregulated
	Transcripts that showed significantly decreased expression in exc-7(csb29);mbl-1(csb30) mutants comparing to in N2.	DESeq	WBPaper00051540:exc-7(csb29);mbl-1(csb30)_downregulated
	Transcripts that showed significantly increased expression in mbl-1(tm1563) comparing to in N2 animals.	Differential expression analysis was performed using the EdgeR package after normalizing read counts and including only those genes with CPM > 1 for at least one out of all samples.	WBPaper00062167:mbl-1(tm1563)_upregulated
	Transcripts that showed significantly decreased expression in mbl-1(syb4345), referred to as mbl-1long(ex7+), comparing to in N2 at L4 larva stage.	DESeq2, Fold change > 2 and FDR < 0.05	WBPaper00066410:mbl-1(syb4345)_downregulated
	Transcripts that showed significantly decreased expression in mbl-1(tm1563) comparing to in N2 animals.	Differential expression analysis was performed using the EdgeR package after normalizing read counts and including only those genes with CPM > 1 for at least one out of all samples.	WBPaper00062167:mbl-1(tm1563)_downregulated
	Transcripts that showed significantly increased expression in mbl-1(tm1563) comparing to in N2 at L4 larva stage.	DESeq2, Fold change > 2 and FDR < 0.05	WBPaper00066410:mbl-1(tm1563)_upregulated
	Transcripts that showed significantly decreased expression in mbl-1(tm1563) comparing to in N2 at L4 larva stage.	DESeq2, Fold change > 2 and FDR < 0.05	WBPaper00066410:mbl-1(tm1563)_downregulated
	Transcripts that showed significantly increased expression in exc-7(csb29);mbl-1(csb30) mutants comparing to in N2.	DESeq	WBPaper00051540:exc-7(csb29);mbl-1(csb30)_upregulated
	Transcripts that showed significantly decreased expression in mbl-1(syb4318), referred to as mbl-1short(ex7-), comparing to in N2 at L4 larva stage.	DESeq2, Fold change > 2 and FDR < 0.05	WBPaper00066410:mbl-1(syb4318)_downregulated
	Transcripts that showed significantly decreased expression in mbl-1(csb30) mutants comparing to in N2.	DESeq	WBPaper00051540:mbl-1(csb30)_downregulated
	Transcripts that showed significantly increased expression in mbl-1(csb30) mutants comparing to in N2.	DESeq	WBPaper00051540:mbl-1(csb30)_upregulated

1 Sequence

• Length: 31695

1 Sequence Ontology Term

• Name: gene

0 Strains

1 Upstream Intergenic Region

• WormBase ID: intergenic_region_chrX_16976144..16978607
• Length (nt): 2464
• Chromosome Location: X: 16976144-16978607
• Organism: Caenorhabditis elegans