WormMine: Gene WBGene00091851

• WormBase Gene ID: WBGene00091851
• Gene Name: Ppa-uba-1
• Sequence Name: PPA02297
• Organism: Pristionchus pacificus
• Automated Description: Predicted to enable several functions, including catalytic activity, acting on a tRNA; flavin adenine dinucleotide binding activity; and ubiquitin-like modifier activating enzyme activity. Predicted to be involved in protein modification process and tRNA splicing, via endonucleolytic cleavage and ligation. Predicted to be part of transcription factor TFIID complex. Is an ortholog of C. elegans uba-1. In C. elegans, uba-1 is involved in several processes, including developmental process involved in reproduction; negative regulation of transcription by RNA polymerase II; and programmed cell death involved in cell development.
• Biotype: SO:0001217
• Genetic Position: :±

1 Organism

• Name: Pristionchus pacificus
• Taxon Id: 54126

0 Synonyms

Genomics

1 Transcripts

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
Transcript:PPA02297.1	PPA02297.1		[unknown]

Other

0 CDSs

0 RNAi Result

0 Allele

0 Chromosome

0 Chromosome Location

2 Data Sets

• WormBaseAcedbConverter
• GO Annotation data set

0 Downstream Intergenic Region

5 Expression Clusters

Regulated By Treatment	Description	Algorithm	Primary Identifier
	Pristionchus pacificus genes up regulated in the dauer versus dauer-exit worms.	The weight parameters were optimized based on MA-plots such that spike-in controls show their expected fold change values. lmFit function was used to fit a linear model to probe intensities across arrays, and differential expression was calculated by empirical Bayes method using the eBayes function. Control of FDR was employed as correction for multiple testing.	WBPaper00041207:PP_dauer_up
Germline ablation	Genes that showed differential expression in the comparision of germline-ablated animals fed on E. coli OP50 versus un-ablated animals fed E. coli OP50.	Differential expression was calculated by empirical Bayes method using the eBayes function, and control of FDR was employed as the multiple testing correction. Authors used cutoff of absolute log2 fold change greater than or equal to 1.5 AND p_value less than or equal to 0.05 to call differentially expressed genes.	WBPaper00041466:PP_germline-ablation_regulated
Bacteria infection: Xenorhabdus nematophila	Pristionchus pacificus Genes with expression levels changed significantly after treatment of Xenorhabdus nematophila.	Differential expression were calculated by empirical eBayes method using eBayes function. P_value <= 0.01 and log2 fold change > 1 were used to call differentially expressed genes in all datasets.	WBPaper00041606:PP_X.nematophila_regulated
Bacteria infection: Serratia marcescens	Pristionchus pacificus Genes with expression levels changed significantly after treatment of Serratia marcescens.	Differential expression were calculated by empirical eBayes method using eBayes function. P_value <= 0.01 and log2 fold change > 1 were used to call differentially expressed genes in all datasets.	WBPaper00041606:PP_S.marcescens_regulated
	Pristionchus pacificus genes down regulated in the dauer versus dauer-exit worms.	The weight parameters were optimized based on MA-plots such that spike-in controls show their expected fold change values. lmFit function was used to fit a linear model to probe intensities across arrays, and differential expression was calculated by empirical Bayes method using the eBayes function. Control of FDR was employed as correction for multiple testing.	WBPaper00041207:PP_dauer_down

0 Expression Patterns

10 GO Annotation

0 Homologues

0 Locations

10 Ontology Annotations

0 Regulates Expr Cluster

0 Sequence

1 Sequence Ontology Term

• Name: gene

0 Strains

0 Upstream Intergenic Region