WormMine: Gene WBGene00101073

• WormBase Gene ID: WBGene00101073
• Gene Name: PPA11519
• Sequence Name: PPA11519
• Brief Description: Ppa-egl-20 encodes a member of the WNT family of developmental signaling proteins that induces, in a redundant manner with other WNT family ligands, the formation of the vulva; expressed in muscle and epidermal cells at the posterior of the worm, making it the first inductive signal for vulva development to be expressed outside of the gonad.
• Organism: Pristionchus pacificus
• Automated Description: Predicted to enable ATP binding activity; ATP hydrolysis activity; and signaling receptor binding activity. Predicted to be involved in Wnt signaling pathway. Predicted to be located in extracellular region. Expressed in tail and vulval precursor cell. Is an ortholog of C. elegans C10G11.8.
• Biotype: SO:0001217
• Genetic Position: :±

1 Organism

• Name: Pristionchus pacificus
• Taxon Id: 54126

0 Synonyms

Genomics

1 Transcripts

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
Transcript:PPA11519.1	PPA11519.1		[unknown]

Other

0 CDSs

0 RNAi Result

2 Allele

• tu364
• tu382

0 Chromosome

0 Chromosome Location

2 Data Sets

• WormBaseAcedbConverter
• GO Annotation data set

0 Downstream Intergenic Region

1 Expression Clusters

Regulated By Treatment	Description	Algorithm	Primary Identifier
Germline ablation	Genes that showed differential expression in the comparision of germline-ablated animals fed on E. coli OP50 versus un-ablated animals fed E. coli OP50.	Differential expression was calculated by empirical Bayes method using the eBayes function, and control of FDR was employed as the multiple testing correction. Authors used cutoff of absolute log2 fold change greater than or equal to 1.5 AND p_value less than or equal to 0.05 to call differentially expressed genes.	WBPaper00041466:PP_germline-ablation_regulated

1 Expression Patterns

• Primary Identifier: Expr12782
• Pattern: Ppa-lin-17 /Fz expression was found in the posterior body region surrounding the rectal area in all larval stages. Coexpression of Ppa-lin-17 /Fz::RFP with Ppa-egl-20 /Wnt::GFP indicates that the two genes have an overlapping expression pattern during larval development that is, however, not completely identical. Low level Ppa-lin-17 /Fz::RFP expression is also seen in more anterior regions including the VPCs during the J3 larval stage. All described expression patterns were highly reproducible and were observed in several independent transgenic lines.

6 GO Annotation

0 Homologues

0 Locations

6 Ontology Annotations

0 Regulates Expr Cluster

0 Sequence

1 Sequence Ontology Term

• Name: gene

0 Strains

0 Upstream Intergenic Region