WormMine: Gene WBGene00222031

• WormBase Gene ID: WBGene00222031
• Gene Name: Bma-unc-44
• Sequence Name: Bm1770
• Organism: Brugia malayi
• Automated Description: Predicted to be involved in signal transduction. Is an ortholog of C. elegans unc-44. In C. elegans, unc-44 is involved in several processes, including axon guidance; establishment or maintenance of cytoskeleton polarity; and regulation of cellular component organization.
• Biotype: SO:0001217
• Genetic Position: :±

1 Organism

• Name: Brugia malayi
• Taxon Id: 6279

0 Synonyms

Genomics

14 Transcripts

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
Transcript:Bm1770a.1	Bm1770a.1		[unknown]
Transcript:Bm1770b.1	Bm1770b.1		[unknown]
Transcript:Bm1770j.1	Bm1770j.1		[unknown]
Transcript:Bm1770k.1	Bm1770k.1		[unknown]
Transcript:Bm1770e.1	Bm1770e.1		[unknown]
Transcript:Bm1770f.1	Bm1770f.1		[unknown]
Transcript:Bm1770c.1	Bm1770c.1		[unknown]
Transcript:Bm1770d.1	Bm1770d.1		[unknown]
Transcript:Bm1770r.1	Bm1770r.1		[unknown]
Transcript:Bm1770p.1	Bm1770p.1		[unknown]
Transcript:Bm1770q.1	Bm1770q.1		[unknown]
Transcript:Bm1770n.1	Bm1770n.1		[unknown]
Transcript:Bm1770o.1	Bm1770o.1		[unknown]
Transcript:Bm1770m.1	Bm1770m.1		[unknown]

Other

14 CDSs

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:Bm1770c	Bm1770c		[unknown]
CDS:Bm1770b	Bm1770b		[unknown]
CDS:Bm1770e	Bm1770e		[unknown]
CDS:Bm1770d	Bm1770d		[unknown]
CDS:Bm1770f	Bm1770f		[unknown]
CDS:Bm1770a	Bm1770a		[unknown]
CDS:Bm1770r	Bm1770r		[unknown]
CDS:Bm1770k	Bm1770k		[unknown]
CDS:Bm1770j	Bm1770j		[unknown]
CDS:Bm1770m	Bm1770m		[unknown]
CDS:Bm1770o	Bm1770o		[unknown]
CDS:Bm1770n	Bm1770n		[unknown]
CDS:Bm1770q	Bm1770q		[unknown]
CDS:Bm1770p	Bm1770p		[unknown]

0 RNAi Result

0 Allele

0 Chromosome

0 Chromosome Location

2 Data Sets

• WormBaseAcedbConverter
• GO Annotation data set

0 Downstream Intergenic Region

4 Expression Clusters

Regulated By Treatment	Description	Algorithm	Primary Identifier
	Transcripts that showed significantly lower expression in adult comparing to in microfilariae.	edgeR v3.28. FDR < 0.05, fold change > 2.	WBPaper00061765:Adult_vs_Micro_Downregulated
	Transcripts that showed significantly lower expression in L4 larva comparing to in microfilariae.	edgeR v3.28. FDR < 0.05, fold change > 2.	WBPaper00061765:L4_vs_Micro_Downregulated
	Transcripts that showed significantly decreased expression in male B. malayi 30 days after infecting gerbils, comparing to L4 male B. malayi animals.	EdgeR(v3.16.5), FDR < 0.05.	WBPaper00051007:downregulated_M30_vs_L4
	Proteins that showed significantly increased expression in parasites exposed to 20-hydroxyecdysone.	An empirical filter of proteins with more than two peptides identified, a P value <0.05 and a greater than two-fold change of differential expression, was applied to the data. The Bonferroni correction was applied to correct the P value for the proteins analyzed.	WBPaper00049261:20-hydroxyecdysone_upregulated_protein

0 Expression Patterns

1 GO Annotation

0 Homologues

0 Locations

1 Ontology Annotations

0 Regulates Expr Cluster

0 Sequence

1 Sequence Ontology Term

• Name: gene

0 Strains

0 Upstream Intergenic Region