WormMine: Gene WBGene00223414

• WormBase Gene ID: WBGene00223414
• Gene Name: Bma-sin-3
• Sequence Name: Bm3153
• Organism: Brugia malayi
• Automated Description: Predicted to enable transcription corepressor activity. Predicted to be involved in regulation of DNA-templated transcription. Is an ortholog of C. elegans sin-3. In C. elegans, sin-3 is involved in several processes, including cell fate specification; nematode male tail mating organ morphogenesis; and vulval development.
• Biotype: SO:0001217
• Genetic Position: :±

1 Organism

• Name: Brugia malayi
• Taxon Id: 6279

0 Synonyms

Genomics

4 Transcripts

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
Transcript:Bm3153c.1	Bm3153c.1		[unknown]
Transcript:Bm3153d.1	Bm3153d.1		[unknown]
Transcript:Bm3153a.1	Bm3153a.1		[unknown]
Transcript:Bm3153b.1	Bm3153b.1		[unknown]

Other

4 CDSs

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:Bm3153b	Bm3153b		[unknown]
CDS:Bm3153a	Bm3153a		[unknown]
CDS:Bm3153d	Bm3153d		[unknown]
CDS:Bm3153c	Bm3153c		[unknown]

0 RNAi Result

0 Allele

0 Chromosome

0 Chromosome Location

2 Data Sets

• WormBaseAcedbConverter
• GO Annotation data set

0 Downstream Intergenic Region

3 Expression Clusters

Regulated By Treatment	Description	Algorithm	Primary Identifier
	Transcripts that showed significantly decreased expression in male B. malayi 120 days after infecting gerbils, comparing to female B. malayi 120 days after infecting gerbils.	EdgeR(v3.16.5), FDR < 0.05.	WBPaper00051007:downregulated_M120_vs_F120
	Transcripts that showed significantly decreased expression after 5 days of 1uM ivermectin exposure.	Differential gene expression analysis between time points and drug concentrations was realized in edgeR (version 3.10.5) through the web interface provided by NetworkAnalyst. Significance was set as an experiment-wide false discovery rate (FDR) <0.20 (after the Benjamini-Hochberg method).	WBPaper00049974:ivermectin_1uM_5-day_downregulated
	Proteins that showed significantly increased expression in parasites exposed to 20-hydroxyecdysone.	An empirical filter of proteins with more than two peptides identified, a P value <0.05 and a greater than two-fold change of differential expression, was applied to the data. The Bonferroni correction was applied to correct the P value for the proteins analyzed.	WBPaper00049261:20-hydroxyecdysone_upregulated_protein

0 Expression Patterns

2 GO Annotation

0 Homologues

0 Locations

2 Ontology Annotations

0 Regulates Expr Cluster

0 Sequence

1 Sequence Ontology Term

• Name: gene

0 Strains

0 Upstream Intergenic Region