Genomics
1 Transcripts
| WormMine ID | Sequence Name | Length (nt) | Chromosome Location |
|---|---|---|---|
| Transcript:Bm3843.1 | Bm3843.1 | [unknown] |
Other
6 Expression Clusters
| Regulated By Treatment | Description | Algorithm | Primary Identifier |
|---|---|---|---|
| Transcripts that showed significantly lower expression in adult comparing to in microfilariae. | edgeR v3.28. FDR < 0.05, fold change > 2. | WBPaper00061765:Adult_vs_Micro_Downregulated | |
| Transcripts that showed significantly increased expression in male B. malayi 120 days after infecting gerbils, comparing to 30 days after infecting gerbils. | EdgeR(v3.16.5), FDR < 0.05. | WBPaper00051007:upregulated_M120_vs_M30 | |
| Transcripts that showed significantly decreased expression in male B. malayi 42 days after infecting gerbils, comparing to 30 days after infecting gerbils. | EdgeR(v3.16.5), FDR < 0.05. | WBPaper00051007:downregulated_M42_vs_M30 | |
| Transcripts that showed significantly increased expression in female B. malayi 120 days after infecting gerbils, comparing to 30 days after infecting gerbils. | EdgeR(v3.16.5), FDR < 0.05. | WBPaper00051007:upregulated_F120_vs_F30 | |
| Transcripts that showed significantly lower expression in L4 larva comparing to in microfilariae. | edgeR v3.28. FDR < 0.05, fold change > 2. | WBPaper00061765:L4_vs_Micro_Downregulated | |
| Transcripts that showed significantly increased expression in male B. malayi 30 days after infecting gerbils, comparing to L4 male B. malayi animals. | EdgeR(v3.16.5), FDR < 0.05. | WBPaper00051007:upregulated_M30_vs_L4 |
3 Expression Patterns
| Remark | Reporter Gene | Primary Identifier | Pattern | Subcellular Localization |
|---|---|---|---|---|
| Assayed in C. elegans. | Expr11950 | Expression was found consistently in hypodermal cells of all lines examined. GFP expression was particularly prominent in the hypodermal cell nuclei hyp5, hyp6, and hyp7 of the head and in the pair of hyp7 cell nuclei in the tail of adult worms. Using sensitive staining techniques for the detection of b-galactosidase activity, expression was also detected in larval stages, again strongly in the head and tail regions. The lacZ expression was less pronounced in the hypodermal cells of the body, with expression being detected in the hypodermal cell nuclei hyp4, hyp5, hyp6, and hyp7 of the head. With prolonged staining (overnight at room temperature) lacZ expression was also observed in the vulval cells of the adult, which are of hypodermal origin, in the adult body wall muscle cells, and in embryonic stages. | ||
| Expr11949 | B. malayi phy-1 is expressed in L1 (microfilaria), at all time points examined throughout L3 and L4 development, and in both adult sexes. | |||
| Expr11517 | Bma-phy-1 is abundantly expressed in all stages examined. |
